Thiol-induced hydroxyl radical formation and scavenger effect of thiocarbamides on hydroxyl radicals

The effects of thiols and thiocarbamides on hydroxyl radical (·OH) formation by the hypoxanthine(HYP)-xanthine oxidase(XOD)-Fe 3+ ·EDTA system were investigated in the range of 0.5–5 mM by colorimetrically measuring salicylate hydroxylation. Thiocarbamides powerfully inhibited the hydroxylation whil...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of inorganic biochemistry 1986-03, Vol.26 (3), p.205-212
Hauptverfasser:	Motohashi, Noriko, Mori, Itsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Phenomena Chemistry, Physical Colorimetry Edetic Acid Free Radicals Hydroxylation Oxidation-Reduction Sulfhydryl Compounds - analysis Superoxides Thiocarbamates - analysis Xanthine Oxidase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!