Tandemly repeated genes encode nucleoside triphosphate hydrolase isoforms secreted into the parasitophorous vacuole of Toxoplasma gondii

The obligate intracellular parasite Toxoplasma gondii produces a nucleoside triphosphate hydrolase (NTPase) (nucleoside-triphosphatase, EC 3.6.1.15) activable by dithiol-containing compounds. We have isolated the genomic DNA for the NTPase from the RH strain of Toxoplasma and determined the nucleoti...

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Veröffentlicht in:	The Journal of biological chemistry 1994-11, Vol.269 (46), p.29252-29260
Hauptverfasser:	Bermudes, D, Peck, K R, Afifi, M A, Beckers, C J, Joiner, K A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Anhydride Hydrolases - genetics Amino Acid Sequence Animals Antibodies, Protozoan - immunology Base Sequence Dithiothreitol - pharmacology DNA, Protozoan Enzyme Activation Genes, Protozoan Mice Molecular Sequence Data Multigene Family Nucleoside-Triphosphatase Precipitin Tests Recombinant Fusion Proteins - immunology Sequence Homology, Amino Acid Toxoplasma - enzymology Toxoplasma - genetics Toxoplasma - physiology Toxoplasma gondii Vacuoles - enzymology
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