Checkpoints of dueling dimers foil death wishes

Recent evidence has emphasized the indispensable role of programmed cell death in the development and maintenance of homeostasis within all multicellular organisms. Genetic and molecular analysis from nematodes to humans has indicated that cellular suicide is highly conserved. Thus, it appears that...

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Veröffentlicht in:	Cell 1994-10, Vol.79 (2), p.189-192
Hauptverfasser:	Oltvai, Zoltán N., Korsmeyer, Stanley J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Apoptosis bcl-2-Associated X Protein Caenorhabditis elegans Proteins Caspase 1 Caspase 2 Caspases Cell Death Cysteine Endopeptidases - physiology Helminth Proteins - physiology Humans Molecular Sequence Data Proteins - physiology Proto-Oncogene Proteins - physiology Proto-Oncogene Proteins c-bcl-2 Tumor Suppressor Protein p53 - physiology
Online-Zugang:	Volltext
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