An Assessment of the Role of Opioid Receptors in the Response to Cannabimimetic Drugs

: Cannabimimetic drugs have been shown to inhibit adenylate cyclase activity in NI8TG2 neuroblastoma cells. This investigation examines the possible role of opioid receptors in the cannabimimetic response. Opioid receptors of the δ subtype were found on N18TG2 membranes using [3H]D‐Ala2‐D‐Leu5‐enkep...

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Veröffentlicht in:	Journal of neurochemistry 1986-06, Vol.46 (6), p.1929-1935
Hauptverfasser:	Devane, William A., Spain, James W., Coscia, Carmine J., Howlett, Allyn C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate cyclase Adenylyl Cyclase Inhibitors Analgesics Animals Biological and medical sciences Cannabinoid drugs Cannabinoids - pharmacology cannabis Cell Line Cyclic AMP Dronabinol - pharmacology Enkephalin, Leucine - analogs & derivatives Enkephalin, Leucine - metabolism Enkephalin, Leucine-2-Alanine Enkephalin, Methionine - analogs & derivatives Enkephalin, Methionine - pharmacology Etorphine - pharmacology Medical sciences mice Morphine - pharmacology Naltrexone - pharmacology Neuroblastoma - enzymology Neuroblastoma cells Neurons - drug effects Neurons - metabolism Neuropharmacology opiates Opioid drugs Pharmacology. Drug treatments Receptors, Opioid - metabolism Receptors, Opioid, delta δ Opioid receptors
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