Triple-helices targeted to the polypurine tract of a murine retrovirus

The all-purine 13-mer oligodeoxyribonucleotide d(GGGGGGAAAAAGA), containing an unusually large block of contiguous guanines, was shown by electrophoresis and thermoelution to form a specific, ‘antiparallel’ complex with the duplex containing the polypurine tract of murine retro viruses. Fourier tran...

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Veröffentlicht in:	Gene 1994-11, Vol.149 (1), p.101-107
Hauptverfasser:	Porumb, H., Dagneaux, C., Letellier, R., Malvy, C., Taillandier, E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-gene antiparallel antisense Base Sequence Cell Line Dunni cells electrophoresis Electrophoresis, Polyacrylamide Gel focus immunoassay Friend murine leukemia virus - genetics Friend retrovirus G + A-containing third strand G + T-containing third strand Guanine - chemistry Hot Temperature Immunoassay infra-red spectroscopy Mice Models, Molecular molecular modeling Molecular Sequence Data Moloney murine leukemia virus - genetics Moloney retrovirus Nucleic Acid Conformation Oligodeoxyribonucleotides - chemistry Purines - chemistry Spectroscopy, Fourier Transform Infrared thermoelution Thymidine - chemistry
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