Isolation and localization of filamin in heart muscle
High‐molecular‐mass protein was isolated from chicken heart muscle. The apparent molecular mass of a single polypeptide chain is similar to that of chicken gizzard filamin: 250–270 kDa. The protein interacts with antibodies against chicken gizzard filamin and induces F‐actin gelation in a concentrat...
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| Veröffentlicht in: | European journal of biochemistry 1986-05, Vol.156 (3), p.619-623 |
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| container_issue | 3 |
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| container_title | European journal of biochemistry |
| container_volume | 156 |
| creator | KOTELIANSKY, Victor E. GLUKHOVA, Marina A. GNEUSHEV, Gennady N. SAMUEL, Jane‐Lyse RAPPAPORT, Lydie |
| description | High‐molecular‐mass protein was isolated from chicken heart muscle. The apparent molecular mass of a single polypeptide chain is similar to that of chicken gizzard filamin: 250–270 kDa. The protein interacts with antibodies against chicken gizzard filamin and induces F‐actin gelation in a concentration‐dependent manner.
Immunofluorescent staining of cardiomyocytes and chicken heart sections with antifilamin antibody demonstrates two types of filamin localization: (a) filamin was located on the sarcomete border in the periphery of the Z‐disk; (b) filamin was found in intercalated disks between cardiomyocytes. |
| doi_str_mv | 10.1111/j.1432-1033.1986.tb09622.x |
| format | Article |
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Immunofluorescent staining of cardiomyocytes and chicken heart sections with antifilamin antibody demonstrates two types of filamin localization: (a) filamin was located on the sarcomete border in the periphery of the Z‐disk; (b) filamin was found in intercalated disks between cardiomyocytes.</description><identifier>ISSN: 0014-2956</identifier><identifier>EISSN: 1432-1033</identifier><identifier>DOI: 10.1111/j.1432-1033.1986.tb09622.x</identifier><identifier>PMID: 3516696</identifier><identifier>CODEN: EJBCAI</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Animals ; Applied sciences ; Chickens ; Chromatography, DEAE-Cellulose ; Contractile Proteins - isolation & purification ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked Immunosorbent Assay ; Exact sciences and technology ; filamin ; Filamins ; Fluorescent Antibody Technique ; Gizzard, Avian ; heart ; Microfilament Proteins - isolation & purification ; Microscopy, Phase-Contrast ; muscles ; Myocardium - analysis ; Myocardium - ultrastructure ; Myofibrils - analysis ; Myofibrils - ultrastructure ; Other techniques and industries</subject><ispartof>European journal of biochemistry, 1986-05, Vol.156 (3), p.619-623</ispartof><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5489-eb6a9477eea661d23ada1ef0a0666c6ea1b1a774a9d11f1e9788b26a583e07ba3</citedby><cites>FETCH-LOGICAL-c5489-eb6a9477eea661d23ada1ef0a0666c6ea1b1a774a9d11f1e9788b26a583e07ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8108359$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3516696$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KOTELIANSKY, Victor E.</creatorcontrib><creatorcontrib>GLUKHOVA, Marina A.</creatorcontrib><creatorcontrib>GNEUSHEV, Gennady N.</creatorcontrib><creatorcontrib>SAMUEL, Jane‐Lyse</creatorcontrib><creatorcontrib>RAPPAPORT, Lydie</creatorcontrib><title>Isolation and localization of filamin in heart muscle</title><title>European journal of biochemistry</title><addtitle>Eur J Biochem</addtitle><description>High‐molecular‐mass protein was isolated from chicken heart muscle. The apparent molecular mass of a single polypeptide chain is similar to that of chicken gizzard filamin: 250–270 kDa. The protein interacts with antibodies against chicken gizzard filamin and induces F‐actin gelation in a concentration‐dependent manner.
Immunofluorescent staining of cardiomyocytes and chicken heart sections with antifilamin antibody demonstrates two types of filamin localization: (a) filamin was located on the sarcomete border in the periphery of the Z‐disk; (b) filamin was found in intercalated disks between cardiomyocytes.</description><subject>Animals</subject><subject>Applied sciences</subject><subject>Chickens</subject><subject>Chromatography, DEAE-Cellulose</subject><subject>Contractile Proteins - isolation & purification</subject><subject>Electrophoresis, Polyacrylamide Gel</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Exact sciences and technology</subject><subject>filamin</subject><subject>Filamins</subject><subject>Fluorescent Antibody Technique</subject><subject>Gizzard, Avian</subject><subject>heart</subject><subject>Microfilament Proteins - isolation & purification</subject><subject>Microscopy, Phase-Contrast</subject><subject>muscles</subject><subject>Myocardium - analysis</subject><subject>Myocardium - ultrastructure</subject><subject>Myofibrils - analysis</subject><subject>Myofibrils - ultrastructure</subject><subject>Other techniques and industries</subject><issn>0014-2956</issn><issn>1432-1033</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkF1LwzAUhoMoc378BKGIeNea07QnjTeiY9PBwAv1Opy2KXak7Ww23Pz1tqzsVgyBhLzPOTk8jF0DD6Bbd8sAIhH6wIUIQCUYrFOuMAyD7REbH6JjNuYcIj9UMZ6yM-eWnHNUKEdsJGLA7jpm8dw1ltZlU3tU555tMrLlz_6hKbyitFSVtdftT0Pt2qs2LrPmgp0UZJ25HM5z9jGbvk9e_MXr83zyuPCzOEqUb1IkFUlpDCFCHgrKCUzBiSNihoYgBZIyIpUDFGCUTJI0RIoTYbhMSZyz233fVdt8bYxb66p0mbGWatNsnJaYcCHj6E8QIpRcoOrA-z2YtY1zrSn0qi0rancauO7l6qXuDereoO7l6kGu3nbFV8Mvm7Qy-aF0sNnlN0NOrvNYtFRnpTtgCfBExP0MD3vsu7Rm948B9Gz69IagxC9jYJXE</recordid><startdate>19860502</startdate><enddate>19860502</enddate><creator>KOTELIANSKY, Victor E.</creator><creator>GLUKHOVA, Marina A.</creator><creator>GNEUSHEV, Gennady N.</creator><creator>SAMUEL, Jane‐Lyse</creator><creator>RAPPAPORT, Lydie</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>C1K</scope><scope>7X8</scope></search><sort><creationdate>19860502</creationdate><title>Isolation and localization of filamin in heart muscle</title><author>KOTELIANSKY, Victor E. ; GLUKHOVA, Marina A. ; GNEUSHEV, Gennady N. ; SAMUEL, Jane‐Lyse ; RAPPAPORT, Lydie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5489-eb6a9477eea661d23ada1ef0a0666c6ea1b1a774a9d11f1e9788b26a583e07ba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Animals</topic><topic>Applied sciences</topic><topic>Chickens</topic><topic>Chromatography, DEAE-Cellulose</topic><topic>Contractile Proteins - isolation & purification</topic><topic>Electrophoresis, Polyacrylamide Gel</topic><topic>Enzyme-Linked Immunosorbent Assay</topic><topic>Exact sciences and technology</topic><topic>filamin</topic><topic>Filamins</topic><topic>Fluorescent Antibody Technique</topic><topic>Gizzard, Avian</topic><topic>heart</topic><topic>Microfilament Proteins - isolation & purification</topic><topic>Microscopy, Phase-Contrast</topic><topic>muscles</topic><topic>Myocardium - analysis</topic><topic>Myocardium - ultrastructure</topic><topic>Myofibrils - analysis</topic><topic>Myofibrils - ultrastructure</topic><topic>Other techniques and industries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KOTELIANSKY, Victor E.</creatorcontrib><creatorcontrib>GLUKHOVA, Marina A.</creatorcontrib><creatorcontrib>GNEUSHEV, Gennady N.</creatorcontrib><creatorcontrib>SAMUEL, Jane‐Lyse</creatorcontrib><creatorcontrib>RAPPAPORT, Lydie</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of biochemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KOTELIANSKY, Victor E.</au><au>GLUKHOVA, Marina A.</au><au>GNEUSHEV, Gennady N.</au><au>SAMUEL, Jane‐Lyse</au><au>RAPPAPORT, Lydie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isolation and localization of filamin in heart muscle</atitle><jtitle>European journal of biochemistry</jtitle><addtitle>Eur J Biochem</addtitle><date>1986-05-02</date><risdate>1986</risdate><volume>156</volume><issue>3</issue><spage>619</spage><epage>623</epage><pages>619-623</pages><issn>0014-2956</issn><eissn>1432-1033</eissn><coden>EJBCAI</coden><abstract>High‐molecular‐mass protein was isolated from chicken heart muscle. The apparent molecular mass of a single polypeptide chain is similar to that of chicken gizzard filamin: 250–270 kDa. The protein interacts with antibodies against chicken gizzard filamin and induces F‐actin gelation in a concentration‐dependent manner.
Immunofluorescent staining of cardiomyocytes and chicken heart sections with antifilamin antibody demonstrates two types of filamin localization: (a) filamin was located on the sarcomete border in the periphery of the Z‐disk; (b) filamin was found in intercalated disks between cardiomyocytes.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>3516696</pmid><doi>10.1111/j.1432-1033.1986.tb09622.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | European journal of biochemistry, 1986-05, Vol.156 (3), p.619-623 |
| issn | 0014-2956 1432-1033 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76803754 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Applied sciences Chickens Chromatography, DEAE-Cellulose Contractile Proteins - isolation & purification Electrophoresis, Polyacrylamide Gel Enzyme-Linked Immunosorbent Assay Exact sciences and technology filamin Filamins Fluorescent Antibody Technique Gizzard, Avian heart Microfilament Proteins - isolation & purification Microscopy, Phase-Contrast muscles Myocardium - analysis Myocardium - ultrastructure Myofibrils - analysis Myofibrils - ultrastructure Other techniques and industries |
| title | Isolation and localization of filamin in heart muscle |
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