Enzyme release into the interstitial space of the isolated rat heart induced by changes in contractile performance

Objective: The aim was to investigate changes in interstitial concentration and release of creatine kinase in isolated perfused rat hearts after an experimental inotropic stimulation or after recovery from a negative inotropic intervention (low Ca2+ or high K+ buffer). Methods: Interstitial transuda...

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Veröffentlicht in:	Cardiovascular research 1994-08, Vol.28 (8), p.1292-1298
Hauptverfasser:	Wienen, Wolfgang, Jüngling, Eberhard, Kammermeier, Helmut
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Calcium - metabolism cardioplegia Cardiotonic agents Cardiovascular system contractile state Creatine Kinase - metabolism enzyme release Extracellular Space - metabolism Female interstitial fluid isoprenaline Isoproterenol - pharmacology low Ca2+ perfusion Medical sciences Myocardial Contraction - physiology myocardium Myocardium - enzymology Myocardium - metabolism Oxygen Consumption - drug effects Perfusion Pharmacology. Drug treatments rat Rats Rats, Sprague-Dawley Stimulation, Chemical stress
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