Effect of fetal and adult bovine albumins on human lymphocyte proliferation in vitro

1. 1. Fetal and adult bovine albumins were isolated and compared with the commercially obtained fraction V of Cohn, in terms of their ability to support cell proliferation, when added as a supplement to serum-free lymphocyte cultures activated with phytohemagglutinin. 2. 2. It was found that fetal albumin is the least efficient of the three proteins in permitting lympho-proliferation. 3. 3. A difference between the kinetics of proliferation of lymphocyte cultures supplemented with albumin and with serum was also observed.