Hormonal parameters in incidental varicoceles and those causing infertility
The gonadotropin responses to a 4-hour infusion of gonadotropin-releasing hormone (GnRH), the prolactin (PRL) responses to a bolus injection of thryotropin-releasing hormone (TRH), and seminal plasma dihydrotestosterone (DHT) levels were assessed before and 6 to 12months after varicocelectomy was pe...
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| Veröffentlicht in: | Fertility and sterility 1986-05, Vol.45 (5), p.692-700 |
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| container_title | Fertility and sterility |
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| creator | Hudson, Robert W. Perez-Marrero, Ramon A. Crawford, Vinton A. McKay, David E. |
| description | The gonadotropin responses to a 4-hour infusion of gonadotropin-releasing hormone (GnRH), the prolactin (PRL) responses to a bolus injection of thryotropin-releasing hormone (TRH), and seminal plasma dihydrotestosterone (DHT) levels were assessed before and 6 to 12months after varicocelectomy was performed in 56 infertile men with varicoceles and sperm densities |
| doi_str_mv | 10.1016/S0015-0282(16)49343-X |
| format | Article |
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The men were divided into four groups, determined by their sperm densities and hormonal parameters. Groups I (18 men) and II (12 men) had sperm densities<10 × 106/ml, and groups HI (16 men) and IV (10 men) had sperm densities of 11 to 30 × 106/ml. The men from groups I and III had excessive preoperative gonadotropin and PRL responses, and lower-than-normal seminal plasma DHT levels. The men in groups II and IV had normal hormonal values. After operation, 12 of the men from group I and 11 from group II had improvements in seminal and hormonal parameters. The other men in these two groups and all of the men in groups II and IV had no changes in seminal and hormonal parameters after operation. This study indicates that an assessment of these hormonal parameters may be useful in predicting which men with varicoceles are likely to have an improvement in sperm density after varicocele repair.</description><identifier>ISSN: 0015-0282</identifier><identifier>EISSN: 1556-5653</identifier><identifier>DOI: 10.1016/S0015-0282(16)49343-X</identifier><identifier>PMID: 3084304</identifier><identifier>CODEN: FESTAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Birth control ; Dihydrotestosterone - metabolism ; Estradiol - blood ; Follicle Stimulating Hormone - blood ; Gonadotropin-Releasing Hormone ; Gynecology. Andrology. Obstetrics ; Hormones - metabolism ; Humans ; Infertility, Male - etiology ; Infertility, Male - metabolism ; Infertility, Male - surgery ; Luteinizing Hormone - blood ; Male ; Medical sciences ; Prolactin - blood ; Semen - metabolism ; Sperm Count ; Sperm Motility ; Sterility. Assisted procreation ; Testosterone - metabolism ; Thyroid Hormones - blood ; Thyrotropin-Releasing Hormone ; Varicocele - complications ; Varicocele - metabolism ; Varicocele - surgery</subject><ispartof>Fertility and sterility, 1986-05, Vol.45 (5), p.692-700</ispartof><rights>1986 American Society for Reproductive Medicine</rights><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c389t-6212445752c9b00045ce2554ac5c128daf9060ea178a7137a630ac4f50f6d66a3</citedby><cites>FETCH-LOGICAL-c389t-6212445752c9b00045ce2554ac5c128daf9060ea178a7137a630ac4f50f6d66a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0015-0282(16)49343-X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8040078$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3084304$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hudson, Robert W.</creatorcontrib><creatorcontrib>Perez-Marrero, Ramon A.</creatorcontrib><creatorcontrib>Crawford, Vinton A.</creatorcontrib><creatorcontrib>McKay, David E.</creatorcontrib><title>Hormonal parameters in incidental varicoceles and those causing infertility</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>The gonadotropin responses to a 4-hour infusion of gonadotropin-releasing hormone (GnRH), the prolactin (PRL) responses to a bolus injection of thryotropin-releasing hormone (TRH), and seminal plasma dihydrotestosterone (DHT) levels were assessed before and 6 to 12months after varicocelectomy was performed in 56 infertile men with varicoceles and sperm densities<30 × 106/ml. The men were divided into four groups, determined by their sperm densities and hormonal parameters. Groups I (18 men) and II (12 men) had sperm densities<10 × 106/ml, and groups HI (16 men) and IV (10 men) had sperm densities of 11 to 30 × 106/ml. The men from groups I and III had excessive preoperative gonadotropin and PRL responses, and lower-than-normal seminal plasma DHT levels. The men in groups II and IV had normal hormonal values. After operation, 12 of the men from group I and 11 from group II had improvements in seminal and hormonal parameters. The other men in these two groups and all of the men in groups II and IV had no changes in seminal and hormonal parameters after operation. This study indicates that an assessment of these hormonal parameters may be useful in predicting which men with varicoceles are likely to have an improvement in sperm density after varicocele repair.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Dihydrotestosterone - metabolism</subject><subject>Estradiol - blood</subject><subject>Follicle Stimulating Hormone - blood</subject><subject>Gonadotropin-Releasing Hormone</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hormones - metabolism</subject><subject>Humans</subject><subject>Infertility, Male - etiology</subject><subject>Infertility, Male - metabolism</subject><subject>Infertility, Male - surgery</subject><subject>Luteinizing Hormone - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Prolactin - blood</subject><subject>Semen - metabolism</subject><subject>Sperm Count</subject><subject>Sperm Motility</subject><subject>Sterility. Assisted procreation</subject><subject>Testosterone - metabolism</subject><subject>Thyroid Hormones - blood</subject><subject>Thyrotropin-Releasing Hormone</subject><subject>Varicocele - complications</subject><subject>Varicocele - metabolism</subject><subject>Varicocele - surgery</subject><issn>0015-0282</issn><issn>1556-5653</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtKAzEUhoMotV4eoTALEV2MnkwuM7MSEW8ouFChu3CaOaORudRkKvTtTW3pVgiE8H8n5-djbMLhggPXl68AXKWQFdkZ1-eyFFKk0x025krpVGkldtl4i-yzgxC-AEDzPBuxkYBCCpBj9vTQ-7bvsEnm6LGlgXxIXBePdRV1Qwx-0DvbW2ooJNhVyfDZB0osLoLrPiJYkx9c44blEdursQl0vLkP2fvd7dvNQ_r8cv94c_2cWlGUQ6oznkmpcpXZchYrSWUpU0qiVZZnRYV1CRoIeV5gzkWOWgBaWSuodaU1ikN2uv537vvvBYXBtC7Efg121C-CyXVeylLKCKo1aH0fgqfazL1r0S8NB7OSaP4kmpUhE19_Es00zk02Cxazlqrt1MZazE82OQaLTe0x2gpbrAAJkBcRu1pjFGX8OPImWEedpcp5soOpevdPkV_Uq43a</recordid><startdate>19860501</startdate><enddate>19860501</enddate><creator>Hudson, Robert W.</creator><creator>Perez-Marrero, Ramon A.</creator><creator>Crawford, Vinton A.</creator><creator>McKay, David E.</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860501</creationdate><title>Hormonal parameters in incidental varicoceles and those causing infertility</title><author>Hudson, Robert W. ; Perez-Marrero, Ramon A. ; Crawford, Vinton A. ; McKay, David E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c389t-6212445752c9b00045ce2554ac5c128daf9060ea178a7137a630ac4f50f6d66a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Dihydrotestosterone - metabolism</topic><topic>Estradiol - blood</topic><topic>Follicle Stimulating Hormone - blood</topic><topic>Gonadotropin-Releasing Hormone</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hormones - metabolism</topic><topic>Humans</topic><topic>Infertility, Male - etiology</topic><topic>Infertility, Male - metabolism</topic><topic>Infertility, Male - surgery</topic><topic>Luteinizing Hormone - blood</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Prolactin - blood</topic><topic>Semen - metabolism</topic><topic>Sperm Count</topic><topic>Sperm Motility</topic><topic>Sterility. Assisted procreation</topic><topic>Testosterone - metabolism</topic><topic>Thyroid Hormones - blood</topic><topic>Thyrotropin-Releasing Hormone</topic><topic>Varicocele - complications</topic><topic>Varicocele - metabolism</topic><topic>Varicocele - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hudson, Robert W.</creatorcontrib><creatorcontrib>Perez-Marrero, Ramon A.</creatorcontrib><creatorcontrib>Crawford, Vinton A.</creatorcontrib><creatorcontrib>McKay, David E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Fertility and sterility</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hudson, Robert W.</au><au>Perez-Marrero, Ramon A.</au><au>Crawford, Vinton A.</au><au>McKay, David E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hormonal parameters in incidental varicoceles and those causing infertility</atitle><jtitle>Fertility and sterility</jtitle><addtitle>Fertil Steril</addtitle><date>1986-05-01</date><risdate>1986</risdate><volume>45</volume><issue>5</issue><spage>692</spage><epage>700</epage><pages>692-700</pages><issn>0015-0282</issn><eissn>1556-5653</eissn><coden>FESTAS</coden><abstract>The gonadotropin responses to a 4-hour infusion of gonadotropin-releasing hormone (GnRH), the prolactin (PRL) responses to a bolus injection of thryotropin-releasing hormone (TRH), and seminal plasma dihydrotestosterone (DHT) levels were assessed before and 6 to 12months after varicocelectomy was performed in 56 infertile men with varicoceles and sperm densities<30 × 106/ml. The men were divided into four groups, determined by their sperm densities and hormonal parameters. Groups I (18 men) and II (12 men) had sperm densities<10 × 106/ml, and groups HI (16 men) and IV (10 men) had sperm densities of 11 to 30 × 106/ml. The men from groups I and III had excessive preoperative gonadotropin and PRL responses, and lower-than-normal seminal plasma DHT levels. The men in groups II and IV had normal hormonal values. After operation, 12 of the men from group I and 11 from group II had improvements in seminal and hormonal parameters. The other men in these two groups and all of the men in groups II and IV had no changes in seminal and hormonal parameters after operation. This study indicates that an assessment of these hormonal parameters may be useful in predicting which men with varicoceles are likely to have an improvement in sperm density after varicocele repair.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3084304</pmid><doi>10.1016/S0015-0282(16)49343-X</doi><tpages>9</tpages></addata></record> |
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| ispartof | Fertility and sterility, 1986-05, Vol.45 (5), p.692-700 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ScienceDirect Journals (5 years ago - present); Alma/SFX Local Collection |
| subjects | Adult Biological and medical sciences Birth control Dihydrotestosterone - metabolism Estradiol - blood Follicle Stimulating Hormone - blood Gonadotropin-Releasing Hormone Gynecology. Andrology. Obstetrics Hormones - metabolism Humans Infertility, Male - etiology Infertility, Male - metabolism Infertility, Male - surgery Luteinizing Hormone - blood Male Medical sciences Prolactin - blood Semen - metabolism Sperm Count Sperm Motility Sterility. Assisted procreation Testosterone - metabolism Thyroid Hormones - blood Thyrotropin-Releasing Hormone Varicocele - complications Varicocele - metabolism Varicocele - surgery |
| title | Hormonal parameters in incidental varicoceles and those causing infertility |
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