Percutaneous Transluminal Angioplasty of the Subclavian Artery in Nonspecific Aortoarteritis: Results of Long-term Follow-up

The results of percutaneous transluminal angioplasty (PTA) of the subclavian artery in nonspecific aortoarteritis (Takayasu disease) are analyzed. Twenty-four patients (15 men, nine women; age range, 18–47 years; mean, 37.1 years) with occlusive disease in 26 subclavian arteries, had symptoms due to...

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Veröffentlicht in:Journal of vascular and interventional radiology 1994-07, Vol.5 (4), p.573-580
Hauptverfasser: Joseph, Santhosh, Mandalam, K. Ravi, Rao, V. Rajanikanth, Gupta, Arun K., Unni, N. Madhavan, Rao, A. Srinivasa, Neelakandhan, Kurar S., Unnikrishnan, Madathipattu, Sandhyamani, Sriramathari
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container_end_page 580
container_issue 4
container_start_page 573
container_title Journal of vascular and interventional radiology
container_volume 5
creator Joseph, Santhosh
Mandalam, K. Ravi
Rao, V. Rajanikanth
Gupta, Arun K.
Unni, N. Madhavan
Rao, A. Srinivasa
Neelakandhan, Kurar S.
Unnikrishnan, Madathipattu
Sandhyamani, Sriramathari
description The results of percutaneous transluminal angioplasty (PTA) of the subclavian artery in nonspecific aortoarteritis (Takayasu disease) are analyzed. Twenty-four patients (15 men, nine women; age range, 18–47 years; mean, 37.1 years) with occlusive disease in 26 subclavian arteries, had symptoms due to vertebrobasilar insufficiency, upper limb claudication, or both. Aortography revealed stenosis in 19 arteries and occlusion in seven. The lesions were focal in 14 arteries (
doi_str_mv 10.1016/S1051-0443(94)71556-6
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Ravi ; Rao, V. Rajanikanth ; Gupta, Arun K. ; Unni, N. Madhavan ; Rao, A. Srinivasa ; Neelakandhan, Kurar S. ; Unnikrishnan, Madathipattu ; Sandhyamani, Sriramathari</creator><creatorcontrib>Joseph, Santhosh ; Mandalam, K. Ravi ; Rao, V. Rajanikanth ; Gupta, Arun K. ; Unni, N. Madhavan ; Rao, A. Srinivasa ; Neelakandhan, Kurar S. ; Unnikrishnan, Madathipattu ; Sandhyamani, Sriramathari</creatorcontrib><description>The results of percutaneous transluminal angioplasty (PTA) of the subclavian artery in nonspecific aortoarteritis (Takayasu disease) are analyzed. Twenty-four patients (15 men, nine women; age range, 18–47 years; mean, 37.1 years) with occlusive disease in 26 subclavian arteries, had symptoms due to vertebrobasilar insufficiency, upper limb claudication, or both. Aortography revealed stenosis in 19 arteries and occlusion in seven. The lesions were focal in 14 arteries (&lt;3 cm) and extensive in 12. Associated lesions involved the brachiocephalic artery in three patients, carotid arteries in five patients, and renal arteries in five patients. Initial technical and clinical success was achieved in 21 of 26 arteries (81%, 17 of 19 stenoses and four of seven occlusions). The maximum follow-up was 82 months (mean, 26 months), during which time restenosis occurred in six arteries, all of which had extensive lesions. The cumulative primary, secondary, and overall patencies were 64%, 82%, and 65%, respectively, as analyzed by means of the life-table method. The cumulative patencies for short- and long-segment lesions were 100% and 50%, respectively ( P = .0113). Minor complications were observed in four of 26 procedures (15%) and included vasospasm (three patients) and transient loss of consciousness (one patient). There were no major complications. PTA is useful for treatment of occlusive disease of the subclavian artery in nonspecific aortoarteritis. 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Twenty-four patients (15 men, nine women; age range, 18–47 years; mean, 37.1 years) with occlusive disease in 26 subclavian arteries, had symptoms due to vertebrobasilar insufficiency, upper limb claudication, or both. Aortography revealed stenosis in 19 arteries and occlusion in seven. The lesions were focal in 14 arteries (&lt;3 cm) and extensive in 12. Associated lesions involved the brachiocephalic artery in three patients, carotid arteries in five patients, and renal arteries in five patients. Initial technical and clinical success was achieved in 21 of 26 arteries (81%, 17 of 19 stenoses and four of seven occlusions). The maximum follow-up was 82 months (mean, 26 months), during which time restenosis occurred in six arteries, all of which had extensive lesions. The cumulative primary, secondary, and overall patencies were 64%, 82%, and 65%, respectively, as analyzed by means of the life-table method. The cumulative patencies for short- and long-segment lesions were 100% and 50%, respectively ( P = .0113). Minor complications were observed in four of 26 procedures (15%) and included vasospasm (three patients) and transient loss of consciousness (one patient). There were no major complications. PTA is useful for treatment of occlusive disease of the subclavian artery in nonspecific aortoarteritis. The procedure is simple and associated with minimal morbidity. 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Aortography revealed stenosis in 19 arteries and occlusion in seven. The lesions were focal in 14 arteries (&lt;3 cm) and extensive in 12. Associated lesions involved the brachiocephalic artery in three patients, carotid arteries in five patients, and renal arteries in five patients. Initial technical and clinical success was achieved in 21 of 26 arteries (81%, 17 of 19 stenoses and four of seven occlusions). The maximum follow-up was 82 months (mean, 26 months), during which time restenosis occurred in six arteries, all of which had extensive lesions. The cumulative primary, secondary, and overall patencies were 64%, 82%, and 65%, respectively, as analyzed by means of the life-table method. The cumulative patencies for short- and long-segment lesions were 100% and 50%, respectively ( P = .0113). Minor complications were observed in four of 26 procedures (15%) and included vasospasm (three patients) and transient loss of consciousness (one patient). There were no major complications. PTA is useful for treatment of occlusive disease of the subclavian artery in nonspecific aortoarteritis. The procedure is simple and associated with minimal morbidity. Long-term results are excellent in focal lesions but are less durable in the presence of more extensive disease.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7949713</pmid><doi>10.1016/S1051-0443(94)71556-6</doi><tpages>8</tpages></addata></record>
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subjects Adolescent
Adult
Angioplasty, Balloon - adverse effects
Arteries, subclavian, 942.1282
Arteries, transluminal angioplasty, 942.1282
Female
Follow-Up Studies
Humans
Male
Middle Aged
Radiography
Recurrence
Subclavian Artery - diagnostic imaging
Takayasu Arteritis - diagnostic imaging
Takayasu Arteritis - therapy
Takayasu arteritis, 942.625
title Percutaneous Transluminal Angioplasty of the Subclavian Artery in Nonspecific Aortoarteritis: Results of Long-term Follow-up
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