The effect of cell-culture conditions on the oligosaccharide structures of secreted glycoproteins

Glycoprotein oligosaccharide structure influences numerous important protein properties. In recent years, a number of studies have demonstrated that cell-culture methodology can significantly affect the oligosaccharide structures of recombinant proteins and antibodies, and, in the past year in parti...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in biotechnology 1994-10, Vol.5 (5), p.546-549
Hauptverfasser:	Andersen, Dana C, Goochee, Charles F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biotechnology Cells, Cultured Culture Techniques - methods Glycoproteins - biosynthesis Glycoproteins - chemistry Glycosylation Humans Mammals Oligosaccharides - biosynthesis Oligosaccharides - chemistry Recombinant Proteins - biosynthesis Transfection
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!