Low lumbar bone mineral density in patients with major depression
Major depression is associated with hypercorticoidism, a risk factor for osteoporosis. However, it is unknown whether depressive disorders are associated with alterations in bone mineral density. The authors measured the density of trabecular bone from the first to the third lumbar vertebra by quant...
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| Veröffentlicht in: | The American journal of psychiatry 1994-11, Vol.151 (11), p.1691-1693 |
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| container_title | The American journal of psychiatry |
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| creator | SCHWEIGER, U DEUSCHL, M KÖRNER, A LAMMERS, C.-H SCHMIDER, J GOTTHARDT, U HOLSBOER, F HEUSER, I |
| description | Major depression is associated with hypercorticoidism, a risk factor for
osteoporosis. However, it is unknown whether depressive disorders are
associated with alterations in bone mineral density. The authors measured
the density of trabecular bone from the first to the third lumbar vertebra
by quantitative computerized tomography in 80 depressed inpatients older
than 40 years and in 57 healthy comparison subjects. An analysis of
covariance model with age as a covariate showed a significant effect of
diagnosis on the dependent variable spinal bone mineral density: depressed
patients had lower values. Other factors could not explain the finding. The
authors conclude that major depression is a significant risk factor for
osteoporosis. |
| doi_str_mv | 10.1176/ajp.151.11.1691 |
| format | Article |
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osteoporosis. However, it is unknown whether depressive disorders are
associated with alterations in bone mineral density. The authors measured
the density of trabecular bone from the first to the third lumbar vertebra
by quantitative computerized tomography in 80 depressed inpatients older
than 40 years and in 57 healthy comparison subjects. An analysis of
covariance model with age as a covariate showed a significant effect of
diagnosis on the dependent variable spinal bone mineral density: depressed
patients had lower values. Other factors could not explain the finding. The
authors conclude that major depression is a significant risk factor for
osteoporosis.</description><identifier>ISSN: 0002-953X</identifier><identifier>EISSN: 1535-7228</identifier><identifier>DOI: 10.1176/ajp.151.11.1691</identifier><identifier>PMID: 7943462</identifier><identifier>CODEN: AJPSAO</identifier><language>eng</language><publisher>Washington, DC: American Psychiatric Publishing</publisher><subject>Adult and adolescent clinical studies ; Age Factors ; Biological and medical sciences ; Body Mass Index ; Bone density ; Bone Density - physiology ; Bones ; Comorbidity ; Depression ; Depressive Disorder - diagnosis ; Depressive Disorder - epidemiology ; Female ; Growth hormones ; History ; Humans ; Lead ; Lumbar Vertebrae - diagnostic imaging ; Male ; Medical disorders ; Medical sciences ; Menopause ; Middle Aged ; Mood disorders ; Osteoporosis ; Osteoporosis - diagnostic imaging ; Osteoporosis - epidemiology ; Physical examinations ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Risk Factors ; Sex Factors ; Space life sciences ; Tomography, X-Ray Computed</subject><ispartof>The American journal of psychiatry, 1994-11, Vol.151 (11), p.1691-1693</ispartof><rights>1995 INIST-CNRS</rights><rights>Copyright American Psychiatric Association Nov 1994</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a444t-dfa59f405300ec127760d7a4ca778ffbd40fee6accba7b08f13df19934be30bc3</citedby><cites>FETCH-LOGICAL-a444t-dfa59f405300ec127760d7a4ca778ffbd40fee6accba7b08f13df19934be30bc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://psychiatryonline.org/doi/epdf/10.1176/ajp.151.11.1691$$EPDF$$P50$$Gappi$$H</linktopdf><linktohtml>$$Uhttps://psychiatryonline.org/doi/full/10.1176/ajp.151.11.1691$$EHTML$$P50$$Gappi$$H</linktohtml><link.rule.ids>314,778,782,2848,21612,27852,27907,27908,77542,77543</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3319633$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7943462$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SCHWEIGER, U</creatorcontrib><creatorcontrib>DEUSCHL, M</creatorcontrib><creatorcontrib>KÖRNER, A</creatorcontrib><creatorcontrib>LAMMERS, C.-H</creatorcontrib><creatorcontrib>SCHMIDER, J</creatorcontrib><creatorcontrib>GOTTHARDT, U</creatorcontrib><creatorcontrib>HOLSBOER, F</creatorcontrib><creatorcontrib>HEUSER, I</creatorcontrib><title>Low lumbar bone mineral density in patients with major depression</title><title>The American journal of psychiatry</title><addtitle>Am J Psychiatry</addtitle><description>Major depression is associated with hypercorticoidism, a risk factor for
osteoporosis. However, it is unknown whether depressive disorders are
associated with alterations in bone mineral density. The authors measured
the density of trabecular bone from the first to the third lumbar vertebra
by quantitative computerized tomography in 80 depressed inpatients older
than 40 years and in 57 healthy comparison subjects. An analysis of
covariance model with age as a covariate showed a significant effect of
diagnosis on the dependent variable spinal bone mineral density: depressed
patients had lower values. Other factors could not explain the finding. The
authors conclude that major depression is a significant risk factor for
osteoporosis.</description><subject>Adult and adolescent clinical studies</subject><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Body Mass Index</subject><subject>Bone density</subject><subject>Bone Density - physiology</subject><subject>Bones</subject><subject>Comorbidity</subject><subject>Depression</subject><subject>Depressive Disorder - diagnosis</subject><subject>Depressive Disorder - epidemiology</subject><subject>Female</subject><subject>Growth hormones</subject><subject>History</subject><subject>Humans</subject><subject>Lead</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Male</subject><subject>Medical disorders</subject><subject>Medical sciences</subject><subject>Menopause</subject><subject>Middle Aged</subject><subject>Mood disorders</subject><subject>Osteoporosis</subject><subject>Osteoporosis - diagnostic imaging</subject><subject>Osteoporosis - epidemiology</subject><subject>Physical examinations</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Space life sciences</subject><subject>Tomography, X-Ray Computed</subject><issn>0002-953X</issn><issn>1535-7228</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>K30</sourceid><recordid>eNqF0U1r3DAQBmBRGpJt2nNOBZOUnurNyJIl6xhC-gELuSTQmxjLEtFiy45kE_Lvo2WXUAKhJzHMoxmJl5AzCmtKpbjE7bSmNc3FmgpFP5AVrVldyqpqPpIVAFSlqtnfE_IppW0ugcnqmBxLxRkX1Ypcbcanol-GFmPRjsEWgw82Yl90NiQ_Pxc-FBPO3oY5FU9-figG3I4xt6doU_Jj-EyOHPbJfjmcp-T-583d9e9yc_vrz_XVpkTO-Vx2DmvlONQMwBpaSSmgk8gNStk413YcnLUCjWlRttA4yjpHlWK8tQxaw07J9_3cKY6Pi02zHnwytu8x2HFJWgrZcOD1fyHNkAreZHj-Bm7HJYb8CV1VwLliaocu3kOUURDQCMGyutwrE8eUonV6in7A-Kwp6F1QOgelc1C50Lug8o2vh7lLO9ju1R-Syf1vhz4mg72LGIxPr4wxqvLezH7sGU6T_-dp72x9AT5FqCA</recordid><startdate>19941101</startdate><enddate>19941101</enddate><creator>SCHWEIGER, U</creator><creator>DEUSCHL, M</creator><creator>KÖRNER, A</creator><creator>LAMMERS, C.-H</creator><creator>SCHMIDER, J</creator><creator>GOTTHARDT, U</creator><creator>HOLSBOER, F</creator><creator>HEUSER, I</creator><general>American Psychiatric Publishing</general><general>American Psychiatric Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>HAWNG</scope><scope>HBMBR</scope><scope>IBDFT</scope><scope>K30</scope><scope>PAAUG</scope><scope>PAWHS</scope><scope>PAWZZ</scope><scope>PAXOH</scope><scope>PBHAV</scope><scope>PBQSW</scope><scope>PBYQZ</scope><scope>PCIWU</scope><scope>PCMID</scope><scope>PCZJX</scope><scope>PDGRG</scope><scope>PDWWI</scope><scope>PETMR</scope><scope>PFVGT</scope><scope>PGXDX</scope><scope>PIHIL</scope><scope>PISVA</scope><scope>PJCTQ</scope><scope>PJTMS</scope><scope>PLCHJ</scope><scope>PMHAD</scope><scope>PNQDJ</scope><scope>POUND</scope><scope>PPLAD</scope><scope>PQAPC</scope><scope>PQCAN</scope><scope>PQCMW</scope><scope>PQEME</scope><scope>PQHKH</scope><scope>PQMID</scope><scope>PQNCT</scope><scope>PQNET</scope><scope>PQSCT</scope><scope>PQSET</scope><scope>PSVJG</scope><scope>PVMQY</scope><scope>PZGFC</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QP</scope><scope>7X8</scope></search><sort><creationdate>19941101</creationdate><title>Low lumbar bone mineral density in patients with major depression</title><author>SCHWEIGER, U ; DEUSCHL, M ; KÖRNER, A ; LAMMERS, C.-H ; SCHMIDER, J ; GOTTHARDT, U ; HOLSBOER, F ; HEUSER, I</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a444t-dfa59f405300ec127760d7a4ca778ffbd40fee6accba7b08f13df19934be30bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult and adolescent clinical studies</topic><topic>Age Factors</topic><topic>Biological and medical sciences</topic><topic>Body Mass Index</topic><topic>Bone density</topic><topic>Bone Density - physiology</topic><topic>Bones</topic><topic>Comorbidity</topic><topic>Depression</topic><topic>Depressive Disorder - diagnosis</topic><topic>Depressive Disorder - epidemiology</topic><topic>Female</topic><topic>Growth hormones</topic><topic>History</topic><topic>Humans</topic><topic>Lead</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Male</topic><topic>Medical disorders</topic><topic>Medical sciences</topic><topic>Menopause</topic><topic>Middle Aged</topic><topic>Mood disorders</topic><topic>Osteoporosis</topic><topic>Osteoporosis - diagnostic imaging</topic><topic>Osteoporosis - epidemiology</topic><topic>Physical examinations</topic><topic>Psychology. 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osteoporosis. However, it is unknown whether depressive disorders are
associated with alterations in bone mineral density. The authors measured
the density of trabecular bone from the first to the third lumbar vertebra
by quantitative computerized tomography in 80 depressed inpatients older
than 40 years and in 57 healthy comparison subjects. An analysis of
covariance model with age as a covariate showed a significant effect of
diagnosis on the dependent variable spinal bone mineral density: depressed
patients had lower values. Other factors could not explain the finding. The
authors conclude that major depression is a significant risk factor for
osteoporosis.</abstract><cop>Washington, DC</cop><pub>American Psychiatric Publishing</pub><pmid>7943462</pmid><doi>10.1176/ajp.151.11.1691</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-953X |
| ispartof | The American journal of psychiatry, 1994-11, Vol.151 (11), p.1691-1693 |
| issn | 0002-953X 1535-7228 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76784045 |
| source | MEDLINE; Psychiatry Legacy Collection Online Journals 1844-1996; Periodicals Index Online |
| subjects | Adult and adolescent clinical studies Age Factors Biological and medical sciences Body Mass Index Bone density Bone Density - physiology Bones Comorbidity Depression Depressive Disorder - diagnosis Depressive Disorder - epidemiology Female Growth hormones History Humans Lead Lumbar Vertebrae - diagnostic imaging Male Medical disorders Medical sciences Menopause Middle Aged Mood disorders Osteoporosis Osteoporosis - diagnostic imaging Osteoporosis - epidemiology Physical examinations Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Risk Factors Sex Factors Space life sciences Tomography, X-Ray Computed |
| title | Low lumbar bone mineral density in patients with major depression |
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