Bone marrow necrosis
Bone marrow necrosis is most frequently diagnosed at postmortem examination. Antemortem diagnosis is still uncommon. In a recent review of world literature, we have found 133 cases of bone marrow necrosis diagnosed during life. It has been observed during the course of a wide variety of diseases, mo...
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| Veröffentlicht in: | American journal of hematology 1994-11, Vol.47 (3), p.225-228 |
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| container_title | American journal of hematology |
| container_volume | 47 |
| creator | Ranaghan, L. Morris, T. C. M. Desai, Z. R. Markey, G. M. |
| description | Bone marrow necrosis is most frequently diagnosed at postmortem examination. Antemortem diagnosis is still uncommon. In a recent review of world literature, we have found 133 cases of bone marrow necrosis diagnosed during life. It has been observed during the course of a wide variety of diseases, most commonly in association with acute and chronic leukemia, carcinoma, malignant lymphoma, infections, and sickle cell disease.
We report two intravitally diagnosed cases of bone marrow necrosis occurring in two patients with high‐grade B‐cell lymphoproliferative disease. These cases are unusual in that both patients had a triad of bone marrow necrosis, high‐grade B‐cell lymphoproliferative disease, and hypercalcemia. Despite chemotherapy, both cases ultimately proved fatal, with progressive involvement of the central nervous system. © 1994 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/ajh.2830470314 |
| format | Article |
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We report two intravitally diagnosed cases of bone marrow necrosis occurring in two patients with high‐grade B‐cell lymphoproliferative disease. These cases are unusual in that both patients had a triad of bone marrow necrosis, high‐grade B‐cell lymphoproliferative disease, and hypercalcemia. Despite chemotherapy, both cases ultimately proved fatal, with progressive involvement of the central nervous system. © 1994 Wiley‐Liss, Inc.</description><identifier>ISSN: 0361-8609</identifier><identifier>EISSN: 1096-8652</identifier><identifier>DOI: 10.1002/ajh.2830470314</identifier><identifier>PMID: 7942788</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Bone Marrow - pathology ; Bone Marrow Diseases - complications ; Bone Marrow Diseases - diagnosis ; Bone Marrow Diseases - epidemiology ; central nervous system ; Female ; high‐grade B‐cell lymphoproliferative disease ; Humans ; hypercalcemia ; Incidence ; Lymphoproliferative Disorders - complications ; Male ; Necrosis ; severe necrosis of bone marrow</subject><ispartof>American journal of hematology, 1994-11, Vol.47 (3), p.225-228</ispartof><rights>Copyright © 1994 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4064-4a88cf12b9bdfd69b4f1e697771c3c1e996cb46894acef4e2afc9997f0574e303</citedby><cites>FETCH-LOGICAL-c4064-4a88cf12b9bdfd69b4f1e697771c3c1e996cb46894acef4e2afc9997f0574e303</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajh.2830470314$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajh.2830470314$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7942788$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ranaghan, L.</creatorcontrib><creatorcontrib>Morris, T. C. M.</creatorcontrib><creatorcontrib>Desai, Z. R.</creatorcontrib><creatorcontrib>Markey, G. M.</creatorcontrib><title>Bone marrow necrosis</title><title>American journal of hematology</title><addtitle>Am J Hematol</addtitle><description>Bone marrow necrosis is most frequently diagnosed at postmortem examination. Antemortem diagnosis is still uncommon. In a recent review of world literature, we have found 133 cases of bone marrow necrosis diagnosed during life. It has been observed during the course of a wide variety of diseases, most commonly in association with acute and chronic leukemia, carcinoma, malignant lymphoma, infections, and sickle cell disease.
We report two intravitally diagnosed cases of bone marrow necrosis occurring in two patients with high‐grade B‐cell lymphoproliferative disease. These cases are unusual in that both patients had a triad of bone marrow necrosis, high‐grade B‐cell lymphoproliferative disease, and hypercalcemia. Despite chemotherapy, both cases ultimately proved fatal, with progressive involvement of the central nervous system. © 1994 Wiley‐Liss, Inc.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Bone Marrow - pathology</subject><subject>Bone Marrow Diseases - complications</subject><subject>Bone Marrow Diseases - diagnosis</subject><subject>Bone Marrow Diseases - epidemiology</subject><subject>central nervous system</subject><subject>Female</subject><subject>high‐grade B‐cell lymphoproliferative disease</subject><subject>Humans</subject><subject>hypercalcemia</subject><subject>Incidence</subject><subject>Lymphoproliferative Disorders - complications</subject><subject>Male</subject><subject>Necrosis</subject><subject>severe necrosis of bone marrow</subject><issn>0361-8609</issn><issn>1096-8652</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDFPwzAQhS0EKqGwITakTmwp59i1fWOpgIIqscBsOc5ZpEqTEhNV_fdN1QrYmO6k9-7Tu8fYDYcxB8ju3fJznBkBUoPg8oQlHFClRk2yU5aAULzfAc_ZRYxLAM6lgQEbaJSZNiZh1w9NTaOVa9tmM6rJt00s4yU7C66KdHWcQ_bx9Pg-m6eLt-eX2XSReglKptIZ4wPPcsyLUCjMZeCkUGvNvfCcEJXPpTIonacgKXPBI6IOMNGSBIghuztw123z1VH8tqsyeqoqV1PTRauVNiBwbxwfjPt8saVg123Zh95aDnZfg-1rsL819Ae3R3KXr6j4sR__7nU86Juyou0_NDt9nf9h7wBRamcb</recordid><startdate>199411</startdate><enddate>199411</enddate><creator>Ranaghan, L.</creator><creator>Morris, T. C. M.</creator><creator>Desai, Z. R.</creator><creator>Markey, G. M.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199411</creationdate><title>Bone marrow necrosis</title><author>Ranaghan, L. ; Morris, T. C. M. ; Desai, Z. R. ; Markey, G. M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4064-4a88cf12b9bdfd69b4f1e697771c3c1e996cb46894acef4e2afc9997f0574e303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Bone Marrow - pathology</topic><topic>Bone Marrow Diseases - complications</topic><topic>Bone Marrow Diseases - diagnosis</topic><topic>Bone Marrow Diseases - epidemiology</topic><topic>central nervous system</topic><topic>Female</topic><topic>high‐grade B‐cell lymphoproliferative disease</topic><topic>Humans</topic><topic>hypercalcemia</topic><topic>Incidence</topic><topic>Lymphoproliferative Disorders - complications</topic><topic>Male</topic><topic>Necrosis</topic><topic>severe necrosis of bone marrow</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ranaghan, L.</creatorcontrib><creatorcontrib>Morris, T. C. M.</creatorcontrib><creatorcontrib>Desai, Z. R.</creatorcontrib><creatorcontrib>Markey, G. M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ranaghan, L.</au><au>Morris, T. C. M.</au><au>Desai, Z. R.</au><au>Markey, G. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bone marrow necrosis</atitle><jtitle>American journal of hematology</jtitle><addtitle>Am J Hematol</addtitle><date>1994-11</date><risdate>1994</risdate><volume>47</volume><issue>3</issue><spage>225</spage><epage>228</epage><pages>225-228</pages><issn>0361-8609</issn><eissn>1096-8652</eissn><abstract>Bone marrow necrosis is most frequently diagnosed at postmortem examination. Antemortem diagnosis is still uncommon. In a recent review of world literature, we have found 133 cases of bone marrow necrosis diagnosed during life. It has been observed during the course of a wide variety of diseases, most commonly in association with acute and chronic leukemia, carcinoma, malignant lymphoma, infections, and sickle cell disease.
We report two intravitally diagnosed cases of bone marrow necrosis occurring in two patients with high‐grade B‐cell lymphoproliferative disease. These cases are unusual in that both patients had a triad of bone marrow necrosis, high‐grade B‐cell lymphoproliferative disease, and hypercalcemia. Despite chemotherapy, both cases ultimately proved fatal, with progressive involvement of the central nervous system. © 1994 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>7942788</pmid><doi>10.1002/ajh.2830470314</doi><tpages>4</tpages></addata></record> |
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| ispartof | American journal of hematology, 1994-11, Vol.47 (3), p.225-228 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library |
| subjects | Adolescent Adult Bone Marrow - pathology Bone Marrow Diseases - complications Bone Marrow Diseases - diagnosis Bone Marrow Diseases - epidemiology central nervous system Female high‐grade B‐cell lymphoproliferative disease Humans hypercalcemia Incidence Lymphoproliferative Disorders - complications Male Necrosis severe necrosis of bone marrow |
| title | Bone marrow necrosis |
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