Extracorporeal life support after heart or lung transplantation
Extracorporeal life support (ECLS) has been used in 10 patients after heart (5 patients), lung (3 patients), and heart-lung (2 patients) transplantation. The age range was 7 months to 55 years. Cardiopulmonary failure leading to institution of ECLS was due to acute postoperative organ malfunction in...
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Veröffentlicht in: | The Annals of thoracic surgery 1994-09, Vol.58 (3), p.754-758 |
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creator | Whyte, Richard I. Deeb, G.Michael McCurry, Kenneth R. Anderson, Harry L. Boiling, Steven F. Bartlett, Robert H. |
description | Extracorporeal life support (ECLS) has been used in 10 patients after heart (5 patients), lung (3 patients), and heart-lung (2 patients) transplantation. The age range was 7 months to 55 years. Cardiopulmonary failure leading to institution of ECLS was due to acute postoperative organ malfunction in 4 patients (2 survived), subacute organ malfunction in 3 patients (none survived), and late rejection or infection in 3 patients (2 survived). Neurologic complications occurred in 3 patients (1 survived) and bleeding, in 5 patients (2 survived). Six patients (60%) were successfully weaned from ECLS, and 4 (40%) survived to leave the hospital. Survival was associated with younger age, shorter duration of ECLS, and longer interval from operation to initiation of ECLS but not to reason for initiating ECLS. Extracorporeal life support is feasible for sustaining both adults and children after heart, lung, or heart-lung transplantation. Best results were obtained in patients with conditions that, in retrospect, were treatable and reversible within days. More experience is needed to predict preoperatively which patients will benefit most from ECLS. |
doi_str_mv | 10.1016/0003-4975(94)90741-2 |
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The age range was 7 months to 55 years. Cardiopulmonary failure leading to institution of ECLS was due to acute postoperative organ malfunction in 4 patients (2 survived), subacute organ malfunction in 3 patients (none survived), and late rejection or infection in 3 patients (2 survived). Neurologic complications occurred in 3 patients (1 survived) and bleeding, in 5 patients (2 survived). Six patients (60%) were successfully weaned from ECLS, and 4 (40%) survived to leave the hospital. Survival was associated with younger age, shorter duration of ECLS, and longer interval from operation to initiation of ECLS but not to reason for initiating ECLS. Extracorporeal life support is feasible for sustaining both adults and children after heart, lung, or heart-lung transplantation. Best results were obtained in patients with conditions that, in retrospect, were treatable and reversible within days. More experience is needed to predict preoperatively which patients will benefit most from ECLS.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/0003-4975(94)90741-2</identifier><identifier>PMID: 7944699</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Cardiopulmonary Resuscitation - methods ; Cardiopulmonary Resuscitation - mortality ; Catheterization, Central Venous ; Catheters, Indwelling ; Child ; Child, Preschool ; Extracorporeal Circulation ; Female ; Follow-Up Studies ; Heart Transplantation ; Heart-Lung Transplantation ; Humans ; Infant ; Life Support Care - methods ; Lung Transplantation ; Male ; Middle Aged ; Postoperative Care ; Postoperative Complications - mortality ; Postoperative Complications - therapy ; Retrospective Studies ; Survival Rate ; Time Factors</subject><ispartof>The Annals of thoracic surgery, 1994-09, Vol.58 (3), p.754-758</ispartof><rights>1994 The Society of Thoracic Surgeons</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c438t-1cb7dc0f45eba34263bcd52deb09ff50ffd77ef6605a2224e1f2c9a9e89c721a3</citedby><cites>FETCH-LOGICAL-c438t-1cb7dc0f45eba34263bcd52deb09ff50ffd77ef6605a2224e1f2c9a9e89c721a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7944699$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Whyte, Richard I.</creatorcontrib><creatorcontrib>Deeb, G.Michael</creatorcontrib><creatorcontrib>McCurry, Kenneth R.</creatorcontrib><creatorcontrib>Anderson, Harry L.</creatorcontrib><creatorcontrib>Boiling, Steven F.</creatorcontrib><creatorcontrib>Bartlett, Robert H.</creatorcontrib><title>Extracorporeal life support after heart or lung transplantation</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Extracorporeal life support (ECLS) has been used in 10 patients after heart (5 patients), lung (3 patients), and heart-lung (2 patients) transplantation. The age range was 7 months to 55 years. Cardiopulmonary failure leading to institution of ECLS was due to acute postoperative organ malfunction in 4 patients (2 survived), subacute organ malfunction in 3 patients (none survived), and late rejection or infection in 3 patients (2 survived). Neurologic complications occurred in 3 patients (1 survived) and bleeding, in 5 patients (2 survived). Six patients (60%) were successfully weaned from ECLS, and 4 (40%) survived to leave the hospital. Survival was associated with younger age, shorter duration of ECLS, and longer interval from operation to initiation of ECLS but not to reason for initiating ECLS. Extracorporeal life support is feasible for sustaining both adults and children after heart, lung, or heart-lung transplantation. Best results were obtained in patients with conditions that, in retrospect, were treatable and reversible within days. More experience is needed to predict preoperatively which patients will benefit most from ECLS.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Cardiopulmonary Resuscitation - methods</subject><subject>Cardiopulmonary Resuscitation - mortality</subject><subject>Catheterization, Central Venous</subject><subject>Catheters, Indwelling</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Extracorporeal Circulation</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Heart Transplantation</subject><subject>Heart-Lung Transplantation</subject><subject>Humans</subject><subject>Infant</subject><subject>Life Support Care - methods</subject><subject>Lung Transplantation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Care</subject><subject>Postoperative Complications - mortality</subject><subject>Postoperative Complications - therapy</subject><subject>Retrospective Studies</subject><subject>Survival Rate</subject><subject>Time Factors</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMtOwzAQRS0EKqXwByBlhWARsB07jjcgVJWHVIkNrC3HGYNRmgTbQfD3uLTqktXM6N55HYROCb4imJTXGOMiZ1LwC8kuJRaM5HQPTQnnNC8pl_tourMcoqMQPlJJkzxBEyEZK6WcotvFd_Ta9H7oPeg2a52FLIxDKmOmbQSfvYNOee-zduzesuTuwtDqLuro-u4YHVjdBjjZxhl6vV-8zB_z5fPD0_xumRtWVDEnphaNwZZxqHXBaFnUpuG0gRpLazm2thECbFlirimlDIilRmoJlTSCEl3M0Plm7uD7zxFCVCsXDLTpEOjHoEQpRFVJmYxsYzS-D8GDVYN3K-1_FMFqzU2toag1FCWZ-uOmaGo7284f6xU0u6YtqKTfbHRIT3458CoYB52BxnkwUTW9-3_BLyKhfa4</recordid><startdate>19940901</startdate><enddate>19940901</enddate><creator>Whyte, Richard I.</creator><creator>Deeb, G.Michael</creator><creator>McCurry, Kenneth R.</creator><creator>Anderson, Harry L.</creator><creator>Boiling, Steven F.</creator><creator>Bartlett, Robert H.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19940901</creationdate><title>Extracorporeal life support after heart or lung transplantation</title><author>Whyte, Richard I. ; Deeb, G.Michael ; McCurry, Kenneth R. ; Anderson, Harry L. ; Boiling, Steven F. ; Bartlett, Robert H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c438t-1cb7dc0f45eba34263bcd52deb09ff50ffd77ef6605a2224e1f2c9a9e89c721a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Cardiopulmonary Resuscitation - methods</topic><topic>Cardiopulmonary Resuscitation - mortality</topic><topic>Catheterization, Central Venous</topic><topic>Catheters, Indwelling</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Extracorporeal Circulation</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Heart Transplantation</topic><topic>Heart-Lung Transplantation</topic><topic>Humans</topic><topic>Infant</topic><topic>Life Support Care - methods</topic><topic>Lung Transplantation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Care</topic><topic>Postoperative Complications - mortality</topic><topic>Postoperative Complications - therapy</topic><topic>Retrospective Studies</topic><topic>Survival Rate</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Whyte, Richard I.</creatorcontrib><creatorcontrib>Deeb, G.Michael</creatorcontrib><creatorcontrib>McCurry, Kenneth R.</creatorcontrib><creatorcontrib>Anderson, Harry L.</creatorcontrib><creatorcontrib>Boiling, Steven F.</creatorcontrib><creatorcontrib>Bartlett, Robert H.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Whyte, Richard I.</au><au>Deeb, G.Michael</au><au>McCurry, Kenneth R.</au><au>Anderson, Harry L.</au><au>Boiling, Steven F.</au><au>Bartlett, Robert H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Extracorporeal life support after heart or lung transplantation</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>1994-09-01</date><risdate>1994</risdate><volume>58</volume><issue>3</issue><spage>754</spage><epage>758</epage><pages>754-758</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Extracorporeal life support (ECLS) has been used in 10 patients after heart (5 patients), lung (3 patients), and heart-lung (2 patients) transplantation. The age range was 7 months to 55 years. Cardiopulmonary failure leading to institution of ECLS was due to acute postoperative organ malfunction in 4 patients (2 survived), subacute organ malfunction in 3 patients (none survived), and late rejection or infection in 3 patients (2 survived). Neurologic complications occurred in 3 patients (1 survived) and bleeding, in 5 patients (2 survived). Six patients (60%) were successfully weaned from ECLS, and 4 (40%) survived to leave the hospital. Survival was associated with younger age, shorter duration of ECLS, and longer interval from operation to initiation of ECLS but not to reason for initiating ECLS. Extracorporeal life support is feasible for sustaining both adults and children after heart, lung, or heart-lung transplantation. Best results were obtained in patients with conditions that, in retrospect, were treatable and reversible within days. More experience is needed to predict preoperatively which patients will benefit most from ECLS.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>7944699</pmid><doi>10.1016/0003-4975(94)90741-2</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adult Age Factors Cardiopulmonary Resuscitation - methods Cardiopulmonary Resuscitation - mortality Catheterization, Central Venous Catheters, Indwelling Child Child, Preschool Extracorporeal Circulation Female Follow-Up Studies Heart Transplantation Heart-Lung Transplantation Humans Infant Life Support Care - methods Lung Transplantation Male Middle Aged Postoperative Care Postoperative Complications - mortality Postoperative Complications - therapy Retrospective Studies Survival Rate Time Factors |
title | Extracorporeal life support after heart or lung transplantation |
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