Prognostic implications of normal exercise tomographic thallium images in patients with angiographic evidence of significant coronary artery disease
This study examines the prognostic implications of normal exercise tomographic thallium images in medically treated patients with angiographic evidence of coronary artery disease (CAD). There were 97 patients aged 60 ± 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (≥50% diameter stenosis)....
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| Veröffentlicht in: | The American journal of cardiology 1994-10, Vol.74 (8), p.769-771 |
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| container_title | The American journal of cardiology |
| container_volume | 74 |
| creator | Fattah, Alia Abdel Kamal, Abdalla M. Pancholy, Samir Ghods, Massroor Russell, Joseph Cassel, David Wasserleben, Valerie Heo, Jaekyeong Iskandrian, Abdulmassih S. |
| description | This study examines the prognostic implications of normal exercise tomographic thallium images in medically treated patients with angiographic evidence of coronary artery disease (CAD). There were 97 patients aged 60 ± 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (≥50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of normal exercise thallium images. These results have important implications in patient management and cost of health delivery. |
| doi_str_mv | 10.1016/0002-9149(94)90431-6 |
| format | Article |
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There were 97 patients aged 60 ± 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (≥50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of normal exercise thallium images. 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There were 97 patients aged 60 ± 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (≥50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of normal exercise thallium images. These results have important implications in patient management and cost of health delivery.</description><subject>Cardiovascular disease</subject><subject>Coronary Angiography</subject><subject>Coronary Disease - complications</subject><subject>Coronary Disease - diagnostic imaging</subject><subject>Coronary Disease - drug therapy</subject><subject>Coronary vessels</subject><subject>Exercise</subject><subject>Exercise Test</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Medical research</subject><subject>Middle Aged</subject><subject>Prognosis</subject><subject>Thallium Radioisotopes</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><issn>0002-9149</issn><issn>1879-1913</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1u1DAUhS3Uqh0KbwCS1QWCRagdO3a8QUIVf1IlWMDa8jg3GVeJndpOoe_BA9fpjGbBgtWVdb9zj3UOQq8oeU8JFVeEkLpSlKu3ir9ThDNaiWdoQ1upKqooO0GbI3KOnqd0W56UNuIMnUnF64aLDfr7I4bBh5SdxW6aR2dNdsEnHHrsQ5zMiOEPROsS4BymMEQz7wqbd2Yc3TIVkRkgYefxXJTgc8K_Xd5h4wd3pOHedeAtrFeTG7zri4_P2IYYvIkP2MQMZXTFxiR4gU57MyZ4eZgX6NfnTz-vv1Y33798u_54U1nW8lxxIw23VCgrtzUlsq9baYgidmtaw5paUKlaYgjUwBoAW1tCmYVOdAwIEZJdoDf7u3MMdwukrCeXLIyj8RCWpKWQUjSCFfDyH_A2LNGXv-makWLFGlUgvodsDClF6PUcSzrxQVOi18b0Wode69CK66fGtCiy14fby3aC7ig6VFT2H_Z7KEncO4g6WbeG2bkINusuuP8bPAIAM6h9</recordid><startdate>19941015</startdate><enddate>19941015</enddate><creator>Fattah, Alia Abdel</creator><creator>Kamal, Abdalla M.</creator><creator>Pancholy, Samir</creator><creator>Ghods, Massroor</creator><creator>Russell, Joseph</creator><creator>Cassel, David</creator><creator>Wasserleben, Valerie</creator><creator>Heo, Jaekyeong</creator><creator>Iskandrian, Abdulmassih S.</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>19941015</creationdate><title>Prognostic implications of normal exercise tomographic thallium images in patients with angiographic evidence of significant coronary artery disease</title><author>Fattah, Alia Abdel ; Kamal, Abdalla M. ; Pancholy, Samir ; Ghods, Massroor ; Russell, Joseph ; Cassel, David ; Wasserleben, Valerie ; Heo, Jaekyeong ; Iskandrian, Abdulmassih S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-4a7a4c169c7b2107f287a090cba8a352617980a0e2e35eec2c013ced6d3e00673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Cardiovascular disease</topic><topic>Coronary Angiography</topic><topic>Coronary Disease - complications</topic><topic>Coronary Disease - diagnostic imaging</topic><topic>Coronary Disease - drug therapy</topic><topic>Coronary vessels</topic><topic>Exercise</topic><topic>Exercise Test</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Medical research</topic><topic>Middle Aged</topic><topic>Prognosis</topic><topic>Thallium Radioisotopes</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fattah, Alia Abdel</creatorcontrib><creatorcontrib>Kamal, Abdalla M.</creatorcontrib><creatorcontrib>Pancholy, Samir</creatorcontrib><creatorcontrib>Ghods, Massroor</creatorcontrib><creatorcontrib>Russell, Joseph</creatorcontrib><creatorcontrib>Cassel, David</creatorcontrib><creatorcontrib>Wasserleben, Valerie</creatorcontrib><creatorcontrib>Heo, Jaekyeong</creatorcontrib><creatorcontrib>Iskandrian, Abdulmassih S.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fattah, Alia Abdel</au><au>Kamal, Abdalla M.</au><au>Pancholy, Samir</au><au>Ghods, Massroor</au><au>Russell, Joseph</au><au>Cassel, David</au><au>Wasserleben, Valerie</au><au>Heo, Jaekyeong</au><au>Iskandrian, Abdulmassih S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic implications of normal exercise tomographic thallium images in patients with angiographic evidence of significant coronary artery disease</atitle><jtitle>The American journal of cardiology</jtitle><addtitle>Am J Cardiol</addtitle><date>1994-10-15</date><risdate>1994</risdate><volume>74</volume><issue>8</issue><spage>769</spage><epage>771</epage><pages>769-771</pages><issn>0002-9149</issn><eissn>1879-1913</eissn><coden>AJCDAG</coden><abstract>This study examines the prognostic implications of normal exercise tomographic thallium images in medically treated patients with angiographic evidence of coronary artery disease (CAD). There were 97 patients aged 60 ± 10 years; 52 had 1-, 30 had 2-, and 15 had 3-vessel CAD (≥50% diameter stenosis). The exercise test was submaximal in 51 patients (53%); ST-segment depression during exercise occurred in 20 patients (21%), and angina during exercise occurred in 23 patients (24%). Most patients (71%) were receiving antianginal therapy. During a mean follow-up of 32 months, only 3 patients had cardiac events: 2 died of cardiac causes and 1 had nonfatal myocardial infarction (event rate 1.1%/year). None of those 3 patients had positive ST response during exercise. Thus, medically treated patients with CAD (including those with multivessel CAD) have a benign prognosis in the presence of normal exercise thallium images. These results have important implications in patient management and cost of health delivery.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7942546</pmid><doi>10.1016/0002-9149(94)90431-6</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | The American journal of cardiology, 1994-10, Vol.74 (8), p.769-771 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Cardiovascular disease Coronary Angiography Coronary Disease - complications Coronary Disease - diagnostic imaging Coronary Disease - drug therapy Coronary vessels Exercise Exercise Test Female Follow-Up Studies Humans Male Medical imaging Medical research Middle Aged Prognosis Thallium Radioisotopes Tomography, Emission-Computed, Single-Photon |
| title | Prognostic implications of normal exercise tomographic thallium images in patients with angiographic evidence of significant coronary artery disease |
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