A review of pruritus
This article reviews the neurophysiology of pruritus and presents evidence that itch is a separate modality from pain, rather than a submodality of pain. The numerous suggested pruritogens are reviewed, and evidence supporting each one is critically examined. The systemic causes of generalized pruri...
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| Veröffentlicht in: | Journal of the American Academy of Dermatology 1986-03, Vol.14 (3), p.375-392 |
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| container_end_page | 392 |
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| container_title | Journal of the American Academy of Dermatology |
| container_volume | 14 |
| creator | Denman, Susan T. |
| description | This article reviews the neurophysiology of pruritus and presents evidence that itch is a separate modality from pain, rather than a submodality of pain. The numerous suggested pruritogens are reviewed, and evidence supporting each one is critically examined. The systemic causes of generalized pruritus are reviewed, with detailed review of the literature on uremic pruritus, cholestatic pruritus, and the pruritus associated with polycythemia vera. The specific treatments used for each of these conditions are reviewed, as well as the use of antihistamines in generalized pruritus. An approach to the workup of a patient with pruritus is suggested. |
| doi_str_mv | 10.1016/S0190-9622(86)70047-9 |
| format | Article |
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The numerous suggested pruritogens are reviewed, and evidence supporting each one is critically examined. The systemic causes of generalized pruritus are reviewed, with detailed review of the literature on uremic pruritus, cholestatic pruritus, and the pruritus associated with polycythemia vera. The specific treatments used for each of these conditions are reviewed, as well as the use of antihistamines in generalized pruritus. 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The numerous suggested pruritogens are reviewed, and evidence supporting each one is critically examined. The systemic causes of generalized pruritus are reviewed, with detailed review of the literature on uremic pruritus, cholestatic pruritus, and the pruritus associated with polycythemia vera. The specific treatments used for each of these conditions are reviewed, as well as the use of antihistamines in generalized pruritus. An approach to the workup of a patient with pruritus is suggested.</description><subject>Antipruritics - therapeutic use</subject><subject>Cholestasis - complications</subject><subject>Histamine - physiology</subject><subject>Humans</subject><subject>Nociceptors - physiopathology</subject><subject>Peptide Hydrolases - physiology</subject><subject>Polycythemia Vera - complications</subject><subject>Prostaglandins - physiology</subject><subject>Pruritus - drug therapy</subject><subject>Pruritus - etiology</subject><subject>Pruritus - physiopathology</subject><subject>Uremia - complications</subject><issn>0190-9622</issn><issn>1097-6787</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkDtPAzEQhC0ECiHQ0UZKhaA4WJ8fa1coinhJkSiA2jL2nnQoyQX7DsS_5_IQLdUWM7O78zE25nDNgeubF-AWCqvL8tLoKwSQWNgDNuRgsdBo8JAN_yzH7CTnDwCwUuCADYTiUls1ZOfTSaKvmr4nTTVZpy7VbZdP2VHlF5nO9nPE3u7vXmePxfz54Wk2nRdBaGgLazCWpL20EUQw_VMYDaI0EYxXoKMMHgOPVkVDtpSlVMIaLqNWFXgTxIhd7PauU_PZUW7dss6BFgu_oqbLDjWiEML0RrUzhtTknKhy61QvffpxHNyGhtvScJuqzmi3peFsnxvvD3TvS4p_qX39Xr_d6dS37Ckkl0NNq0CxThRaF5v6nwu_9q9rxA</recordid><startdate>19860301</startdate><enddate>19860301</enddate><creator>Denman, Susan T.</creator><general>Mosby, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19860301</creationdate><title>A review of pruritus</title><author>Denman, Susan T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-987d2e6a49d03c80167d87748d08a506d4ca7c1d95d8e92424539814d65f0a8c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Antipruritics - therapeutic use</topic><topic>Cholestasis - complications</topic><topic>Histamine - physiology</topic><topic>Humans</topic><topic>Nociceptors - physiopathology</topic><topic>Peptide Hydrolases - physiology</topic><topic>Polycythemia Vera - complications</topic><topic>Prostaglandins - physiology</topic><topic>Pruritus - drug therapy</topic><topic>Pruritus - etiology</topic><topic>Pruritus - physiopathology</topic><topic>Uremia - complications</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Denman, Susan T.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Academy of Dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Denman, Susan T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A review of pruritus</atitle><jtitle>Journal of the American Academy of Dermatology</jtitle><addtitle>J Am Acad Dermatol</addtitle><date>1986-03-01</date><risdate>1986</risdate><volume>14</volume><issue>3</issue><spage>375</spage><epage>392</epage><pages>375-392</pages><issn>0190-9622</issn><eissn>1097-6787</eissn><abstract>This article reviews the neurophysiology of pruritus and presents evidence that itch is a separate modality from pain, rather than a submodality of pain. 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| fulltext | fulltext |
| identifier | ISSN: 0190-9622 |
| ispartof | Journal of the American Academy of Dermatology, 1986-03, Vol.14 (3), p.375-392 |
| issn | 0190-9622 1097-6787 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76773338 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Antipruritics - therapeutic use Cholestasis - complications Histamine - physiology Humans Nociceptors - physiopathology Peptide Hydrolases - physiology Polycythemia Vera - complications Prostaglandins - physiology Pruritus - drug therapy Pruritus - etiology Pruritus - physiopathology Uremia - complications |
| title | A review of pruritus |
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