alpha-Difluoromethylornithine delays behavioral recovery and induces decompensation after unilateral labyrinthectomy

Biochemical and pharmacologic studies suggest a role for the ornithine decarboxylase-polyamine system as a modulator of behavioral changes during vestibular compensation. alpha-Difluoromethylornithine specifically blocks the rate-limiting step of polyamine biosynthesis. To assess the effects of alph...

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Veröffentlicht in:	Otolaryngology-head and neck surgery 1994-10, Vol.111 (4), p.377-384
Hauptverfasser:	Backous, D D, Henley, C M, Dunn, J K, Jenkins, H A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Ear, Inner - surgery Eflornithine - pharmacology Guinea Pigs Ornithine Decarboxylase - metabolism Ornithine Decarboxylase Inhibitors Polyamines - metabolism Posture Random Allocation Space life sciences
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