The effect of β-adrenergic stimulation on the bladder and urethra following radical hysterectomy

The effect of two β-adrenergic stimulating agents on bladder and urethral function was assessed in 16 patients 3 weeks after radical hysterectomy for carcinoma of the cervix. Urodynamic evaluation was performed before and after inhalation of metaproterenol by metered dose inhaler in 10 patients and...

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Veröffentlicht in:Gynecologic oncology 1986-03, Vol.23 (3), p.267-274
Hauptverfasser: Kerr-Wilson, R.H.J., Orr, J.W., Shingleton, H.M., Hatch, K.D., Trammel, M.W.
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container_end_page 274
container_issue 3
container_start_page 267
container_title Gynecologic oncology
container_volume 23
creator Kerr-Wilson, R.H.J.
Orr, J.W.
Shingleton, H.M.
Hatch, K.D.
Trammel, M.W.
description The effect of two β-adrenergic stimulating agents on bladder and urethral function was assessed in 16 patients 3 weeks after radical hysterectomy for carcinoma of the cervix. Urodynamic evaluation was performed before and after inhalation of metaproterenol by metered dose inhaler in 10 patients and injection of 0.25 mg of terbutaline sc in 6 patients. Although no change was observed following administration of metaproterenol, a significant decrease in maximum urethral pressure and urethral closure pressure, and a significant increase in volume of urine voided was found after administration of terbutaline. These results suggest that β-sympathomimetic agents may benefit those patients with bladder dysfunction following radical hysterectomy.
doi_str_mv 10.1016/0090-8258(86)90126-5
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subjects Adrenergic beta-Agonists - pharmacology
Adult
Female
Humans
Hysterectomy - adverse effects
Metaproterenol - pharmacology
Middle Aged
Terbutaline - pharmacology
Urethra - drug effects
Urethra - physiopathology
Urinary Bladder - drug effects
Urinary Bladder - physiopathology
Urodynamics
Uterine Cervical Neoplasms - physiopathology
Uterine Cervical Neoplasms - surgery
title The effect of β-adrenergic stimulation on the bladder and urethra following radical hysterectomy
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