Clinical patterns and electrophysiological findings in retinal pigment epithelium diseases: does a correlation exist?

At present it is difficult to distinguish those human chorioretinal diseases in which the retinal pigment epithelium (RPE) is the primary site of dysfunction. This difficulty is caused by several factors such as scarcity of biochemical and histological information and a lack of correlation of basic...

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Veröffentlicht in:Documenta ophthalmologica 1986-01, Vol.62 (1), p.73-79
Hauptverfasser: PONTE, F, ANASTASI, M, CILLINO, S
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ANASTASI, M
CILLINO, S
description At present it is difficult to distinguish those human chorioretinal diseases in which the retinal pigment epithelium (RPE) is the primary site of dysfunction. This difficulty is caused by several factors such as scarcity of biochemical and histological information and a lack of correlation of basic science information available with the clinical body of knowledge. In the present study we examined 134 eyes at early or late stages of hereditary diseases involving the RPE. We tried to distinguish primary RPE involvement by using standard ERG (a- and b-wave) and EOG testing. We conclude that in general primary RPE damage can be better assessed by current electrophysiology in those diseases which seem to remain localized at the RPE level for a long time.
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subjects Adolescent
Adult
Aged
Biological and medical sciences
Child
Electrooculography
Electroretinography
Female
Humans
Male
Medical sciences
Middle Aged
Ophthalmology
Pigment Epithelium of Eye
Retinal Diseases - genetics
Retinal Diseases - physiopathology
Retinopathies
title Clinical patterns and electrophysiological findings in retinal pigment epithelium diseases: does a correlation exist?
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