Sequence, expression and modeled structure of an aspartic proteinase from the human malaria parasite Plasmodium falciparum

A clone encoding the aspartic proteinase (PFAPD) from Plasmodium falciparum strain HB3 was obtained during the course of a project designed to sequence and identify the protein coding regions of the parasite's genome. The protein encoded by the clone contains a sequence identical to the N-termi...

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Veröffentlicht in:	Molecular and biochemical parasitology 1994-04, Vol.64 (2), p.177-190
Hauptverfasser:	Dame, John B., Reddy, G.Roman, Yowell, Charles A., Dunn, Ben M., Kay, John, Berry, Colin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Aspartic Acid Endopeptidases - chemistry Aspartic Acid Endopeptidases - genetics Aspartic Acid Endopeptidases - metabolism Aspartic proteinase Base Sequence Binding Sites Biochemistry. Physiology. Immunology. Molecular biology Biological and medical sciences Cloning, Molecular Digestive vacuole DNA, Protozoan - genetics Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Gene Expression Genes, Protozoan Haemoglobinase Humans Invertebrates Malaria Models, Molecular Molecular Sequence Data Multigene Family Plasmodium falciparum Plasmodium falciparum - enzymology Plasmodium falciparum - genetics Protein Folding Protozoa Recombinant protein Sequence Homology, Amino Acid Substrate Specificity
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