Stability of Aspirin in Solid Mixtures
It has been shown that the degradation of aspirin in mixtures may be monitored by thermal analytical techniques. The methodology employed differential scanning calorimetry and thermal gravimetric analysis by standard techniques providing simple and rapid analysis for screening the stability of aspir...
Gespeichert in:
| Veröffentlicht in: | Journal of pharmaceutical sciences 1986-01, Vol.75 (1), p.97-101 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 101 |
|---|---|
| container_issue | 1 |
| container_start_page | 97 |
| container_title | Journal of pharmaceutical sciences |
| container_volume | 75 |
| creator | Ager, David J. Alexander, Kenneth S. Bhatti, Asif S. Blackburn, John S. Dollimore, David Koogan, Timothy S. Mooseman, Keith A. Muhvic, George M. Sims, Belinda Webb, Victoria J. |
| description | It has been shown that the degradation of aspirin in mixtures may be monitored by thermal analytical techniques. The methodology employed differential scanning calorimetry and thermal gravimetric analysis by standard techniques providing simple and rapid analysis for screening the stability of aspirin in mixtures. The degradation was found to depend on the nature of the additive but, in particular, the presence of acidic or basic groups within its structure. |
| doi_str_mv | 10.1002/jps.2600750124 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76763370</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0022354915469771</els_id><sourcerecordid>76763370</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4564-3994242063df181c85bf452997c9c6109173ae84534bdae6c13605fc203eac0e3</originalsourceid><addsrcrecordid>eNqFkEtPGzEURq0KRFPotjukLBC7Cdfv8ZKkQIloQQqoS8vx3JFMJ5nUngD593U1URALhGTJi3u--ziEfKMwogDs7HGVRkwBaAmUiU9kQCWDQgHVe2SQAVZwKcxn8iWlRwBQIOUBOeBGloaqATmddW4emtBthm09PE-rEMNymN-sbUI1_BleunXEdET2a9ck_Lr9D8nD5cX95Edxc3t1PTm_KbyQShTcGMEEA8WrmpbUl3JeC8mM0d54RcFQzR2WQnIxrxwqT3leqPYMODoPyA_Jad93Fdu_a0ydXYTksWncEtt1slppxbmGDI560Mc2pYi1XcWwcHFjKdj_YmwWY1_F5MDxtvN6vsBqh29N5PrJtu6Sd00d3dKHtMNKzVWenDHTY8-hwc0HQ-30bvZmhaLPhtThyy7r4h-rNNfS_v51ZcdqXE4n99_tJPNlz2M2_hQw2uQDLj1WIaLvbNWG9679B8U8mrM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76763370</pqid></control><display><type>article</type><title>Stability of Aspirin in Solid Mixtures</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><source>Alma/SFX Local Collection</source><creator>Ager, David J. ; Alexander, Kenneth S. ; Bhatti, Asif S. ; Blackburn, John S. ; Dollimore, David ; Koogan, Timothy S. ; Mooseman, Keith A. ; Muhvic, George M. ; Sims, Belinda ; Webb, Victoria J.</creator><creatorcontrib>Ager, David J. ; Alexander, Kenneth S. ; Bhatti, Asif S. ; Blackburn, John S. ; Dollimore, David ; Koogan, Timothy S. ; Mooseman, Keith A. ; Muhvic, George M. ; Sims, Belinda ; Webb, Victoria J.</creatorcontrib><description>It has been shown that the degradation of aspirin in mixtures may be monitored by thermal analytical techniques. The methodology employed differential scanning calorimetry and thermal gravimetric analysis by standard techniques providing simple and rapid analysis for screening the stability of aspirin in mixtures. The degradation was found to depend on the nature of the additive but, in particular, the presence of acidic or basic groups within its structure.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600750124</identifier><identifier>PMID: 3958916</identifier><identifier>CODEN: JPMSAE</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Aspirin - analysis ; Biological and medical sciences ; Calorimetry, Differential Scanning ; Chromatography, Gas ; Drug Stability ; General pharmacology ; Indicators and Reagents ; Magnetic Resonance Spectroscopy ; Medical sciences ; Pharmacology. Drug treatments ; Physicochemical properties. Structure-activity relationships ; Tablets ; Temperature</subject><ispartof>Journal of pharmaceutical sciences, 1986-01, Vol.75 (1), p.97-101</ispartof><rights>1986 Wiley-Liss, Inc., A Wiley Company</rights><rights>Copyright © 1986 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4564-3994242063df181c85bf452997c9c6109173ae84534bdae6c13605fc203eac0e3</citedby><cites>FETCH-LOGICAL-c4564-3994242063df181c85bf452997c9c6109173ae84534bdae6c13605fc203eac0e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600750124$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600750124$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,781,785,1418,4025,27928,27929,27930,45579,45580</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8736633$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3958916$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ager, David J.</creatorcontrib><creatorcontrib>Alexander, Kenneth S.</creatorcontrib><creatorcontrib>Bhatti, Asif S.</creatorcontrib><creatorcontrib>Blackburn, John S.</creatorcontrib><creatorcontrib>Dollimore, David</creatorcontrib><creatorcontrib>Koogan, Timothy S.</creatorcontrib><creatorcontrib>Mooseman, Keith A.</creatorcontrib><creatorcontrib>Muhvic, George M.</creatorcontrib><creatorcontrib>Sims, Belinda</creatorcontrib><creatorcontrib>Webb, Victoria J.</creatorcontrib><title>Stability of Aspirin in Solid Mixtures</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>It has been shown that the degradation of aspirin in mixtures may be monitored by thermal analytical techniques. The methodology employed differential scanning calorimetry and thermal gravimetric analysis by standard techniques providing simple and rapid analysis for screening the stability of aspirin in mixtures. The degradation was found to depend on the nature of the additive but, in particular, the presence of acidic or basic groups within its structure.</description><subject>Aspirin - analysis</subject><subject>Biological and medical sciences</subject><subject>Calorimetry, Differential Scanning</subject><subject>Chromatography, Gas</subject><subject>Drug Stability</subject><subject>General pharmacology</subject><subject>Indicators and Reagents</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Physicochemical properties. Structure-activity relationships</subject><subject>Tablets</subject><subject>Temperature</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPGzEURq0KRFPotjukLBC7Cdfv8ZKkQIloQQqoS8vx3JFMJ5nUngD593U1URALhGTJi3u--ziEfKMwogDs7HGVRkwBaAmUiU9kQCWDQgHVe2SQAVZwKcxn8iWlRwBQIOUBOeBGloaqATmddW4emtBthm09PE-rEMNymN-sbUI1_BleunXEdET2a9ck_Lr9D8nD5cX95Edxc3t1PTm_KbyQShTcGMEEA8WrmpbUl3JeC8mM0d54RcFQzR2WQnIxrxwqT3leqPYMODoPyA_Jad93Fdu_a0ydXYTksWncEtt1slppxbmGDI560Mc2pYi1XcWwcHFjKdj_YmwWY1_F5MDxtvN6vsBqh29N5PrJtu6Sd00d3dKHtMNKzVWenDHTY8-hwc0HQ-30bvZmhaLPhtThyy7r4h-rNNfS_v51ZcdqXE4n99_tJPNlz2M2_hQw2uQDLj1WIaLvbNWG9679B8U8mrM</recordid><startdate>198601</startdate><enddate>198601</enddate><creator>Ager, David J.</creator><creator>Alexander, Kenneth S.</creator><creator>Bhatti, Asif S.</creator><creator>Blackburn, John S.</creator><creator>Dollimore, David</creator><creator>Koogan, Timothy S.</creator><creator>Mooseman, Keith A.</creator><creator>Muhvic, George M.</creator><creator>Sims, Belinda</creator><creator>Webb, Victoria J.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley</general><general>American Pharmaceutical Association</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198601</creationdate><title>Stability of Aspirin in Solid Mixtures</title><author>Ager, David J. ; Alexander, Kenneth S. ; Bhatti, Asif S. ; Blackburn, John S. ; Dollimore, David ; Koogan, Timothy S. ; Mooseman, Keith A. ; Muhvic, George M. ; Sims, Belinda ; Webb, Victoria J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4564-3994242063df181c85bf452997c9c6109173ae84534bdae6c13605fc203eac0e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Aspirin - analysis</topic><topic>Biological and medical sciences</topic><topic>Calorimetry, Differential Scanning</topic><topic>Chromatography, Gas</topic><topic>Drug Stability</topic><topic>General pharmacology</topic><topic>Indicators and Reagents</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Physicochemical properties. Structure-activity relationships</topic><topic>Tablets</topic><topic>Temperature</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ager, David J.</creatorcontrib><creatorcontrib>Alexander, Kenneth S.</creatorcontrib><creatorcontrib>Bhatti, Asif S.</creatorcontrib><creatorcontrib>Blackburn, John S.</creatorcontrib><creatorcontrib>Dollimore, David</creatorcontrib><creatorcontrib>Koogan, Timothy S.</creatorcontrib><creatorcontrib>Mooseman, Keith A.</creatorcontrib><creatorcontrib>Muhvic, George M.</creatorcontrib><creatorcontrib>Sims, Belinda</creatorcontrib><creatorcontrib>Webb, Victoria J.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ager, David J.</au><au>Alexander, Kenneth S.</au><au>Bhatti, Asif S.</au><au>Blackburn, John S.</au><au>Dollimore, David</au><au>Koogan, Timothy S.</au><au>Mooseman, Keith A.</au><au>Muhvic, George M.</au><au>Sims, Belinda</au><au>Webb, Victoria J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stability of Aspirin in Solid Mixtures</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1986-01</date><risdate>1986</risdate><volume>75</volume><issue>1</issue><spage>97</spage><epage>101</epage><pages>97-101</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><coden>JPMSAE</coden><abstract>It has been shown that the degradation of aspirin in mixtures may be monitored by thermal analytical techniques. The methodology employed differential scanning calorimetry and thermal gravimetric analysis by standard techniques providing simple and rapid analysis for screening the stability of aspirin in mixtures. The degradation was found to depend on the nature of the additive but, in particular, the presence of acidic or basic groups within its structure.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>3958916</pmid><doi>10.1002/jps.2600750124</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-3549 |
| ispartof | Journal of pharmaceutical sciences, 1986-01, Vol.75 (1), p.97-101 |
| issn | 0022-3549 1520-6017 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76763370 |
| source | MEDLINE; Wiley Online Library All Journals; Alma/SFX Local Collection |
| subjects | Aspirin - analysis Biological and medical sciences Calorimetry, Differential Scanning Chromatography, Gas Drug Stability General pharmacology Indicators and Reagents Magnetic Resonance Spectroscopy Medical sciences Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Tablets Temperature |
| title | Stability of Aspirin in Solid Mixtures |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-15T17%3A47%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Stability%20of%20Aspirin%20in%20Solid%20Mixtures&rft.jtitle=Journal%20of%20pharmaceutical%20sciences&rft.au=Ager,%20David%20J.&rft.date=1986-01&rft.volume=75&rft.issue=1&rft.spage=97&rft.epage=101&rft.pages=97-101&rft.issn=0022-3549&rft.eissn=1520-6017&rft.coden=JPMSAE&rft_id=info:doi/10.1002/jps.2600750124&rft_dat=%3Cproquest_cross%3E76763370%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76763370&rft_id=info:pmid/3958916&rft_els_id=S0022354915469771&rfr_iscdi=true |