Differential effects of guanosine 5′- O-(3-thiotriphosphate) (GTPγS) on the 2-[ 125I]iodomelatonin binding sites in the chicken bursa of Fabricius and spleen

Effects of 10 and 50 μmol/l guanosine 5′- O-(3-thiotriphosphate) (GTPγS) on 2-[ 125I]iodomelatonin binding in the chicken bursa of Fabricius and spleen were tested. In the chicken bursa of Fabricius, GTPγS increased the K d of 2-[ 125I]iodomelatonin binding sites without affecting the B max value. I...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1994-05, Vol.173 (1), p.167-171
Hauptverfasser:	Poon, A.M.S., Pang, S.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bursa of Fabricius - drug effects Bursa of Fabricius - metabolism Chickens Down-regulation Down-Regulation - drug effects Fundamental and applied biological sciences. Psychology Fundamental immunology G protein melatonin receptor subtypes Guanine nucleotide Guanosine 5'-O-(3-Thiotriphosphate) - pharmacology Guanosine Triphosphate - pharmacology Immune system Immunobiology In Vitro Techniques Iodine Radioisotopes Kinetics Lymphoid organs: ontogeny, organization, homing phenomenon Melatonin - metabolism Membranes - drug effects Membranes - metabolism Pineal gland Receptors, Cell Surface - drug effects Receptors, Cell Surface - metabolism Receptors, Melatonin Spleen - drug effects Spleen - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!