Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion
A new method for the rapid determination of red-blood-cell mass (RCM) in infants needing blood transfusion is described. RCM is estimated from the fall in the baby's fetal haemoglobin level resulting from transfusion of a known mass of adult-haemoglobin-containing red cells. In severe blood los...
Gespeichert in:
| Veröffentlicht in: | The Lancet (British edition) 1986-04, Vol.1 (8486), p.882-884 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 884 |
|---|---|
| container_issue | 8486 |
| container_start_page | 882 |
| container_title | The Lancet (British edition) |
| container_volume | 1 |
| creator | PHILLIPS, H. M HOLLAND, B. M ABDEL ABDEL-MOIZ SUHEIR FAYED JONES, J. G TURNER, T. L WARDROP, C. A. J COCKBURN, F |
| description | A new method for the rapid determination of red-blood-cell mass (RCM) in infants needing blood transfusion is described. RCM is estimated from the fall in the baby's fetal haemoglobin level resulting from transfusion of a known mass of adult-haemoglobin-containing red cells. In severe blood loss and refractory anaemias in preterm infants, in addition to the red-cell deficit, the plasma volume is low, leading to a falsely high haematocrit of about 0.30, which conceals a deficiency of 50-70% in circulating red cells. Red-cell transfusion in such infants based on haematocrit often fails to restore RCM to normal, leading to repeated transfusions. The frequency of transfusions may be reduced by giving enough red cells fully to correct the deficiency based on RCM estimation. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_76759789</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76759789</sourcerecordid><originalsourceid>FETCH-LOGICAL-p167t-442dd96b9576cb5a2673c65ba79f656b35d852c6966efec976ae09451eadde6e3</originalsourceid><addsrcrecordid>eNo9kE9LxDAQxYMo67r6EYQcxFshbZNJc5T1Lyx4UfBWJs10ydKma9Me_PZGLZ4eb-bHY96csHUutcyU1B-nbC1yKTLQJZyzixgPQggJQq3Yqqi0KJVas8M9TTT2PuDkh8CHlo_ksoa6jvcYI_eBJ6EYewoTx-DSOOCefm2ik6He4w9n0XqKPBA5H_bcdsPg-DRiiO0cU_glO2uxi3S16Ia9Pz68bZ-z3evTy_Zulx1z0FMmZeGcAWuUhsYqLNL9DSiL2rSgwJbKVapowABQS43RgCSMVDmhcwRUbtjtX-5xHD5nilPd-_jTCAMNc6w1aGV0ZRJ4vYCz7cnVx9H3OH7Vy3PS_mbZY2ywa1OVxsd_rAKQVVmU39r_b8Y</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76759789</pqid></control><display><type>article</type><title>Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>PHILLIPS, H. M ; HOLLAND, B. M ; ABDEL ABDEL-MOIZ ; SUHEIR FAYED ; JONES, J. G ; TURNER, T. L ; WARDROP, C. A. J ; COCKBURN, F</creator><creatorcontrib>PHILLIPS, H. M ; HOLLAND, B. M ; ABDEL ABDEL-MOIZ ; SUHEIR FAYED ; JONES, J. G ; TURNER, T. L ; WARDROP, C. A. J ; COCKBURN, F</creatorcontrib><description>A new method for the rapid determination of red-blood-cell mass (RCM) in infants needing blood transfusion is described. RCM is estimated from the fall in the baby's fetal haemoglobin level resulting from transfusion of a known mass of adult-haemoglobin-containing red cells. In severe blood loss and refractory anaemias in preterm infants, in addition to the red-cell deficit, the plasma volume is low, leading to a falsely high haematocrit of about 0.30, which conceals a deficiency of 50-70% in circulating red cells. Red-cell transfusion in such infants based on haematocrit often fails to restore RCM to normal, leading to repeated transfusions. The frequency of transfusions may be reduced by giving enough red cells fully to correct the deficiency based on RCM estimation.</description><identifier>ISSN: 0140-6736</identifier><identifier>EISSN: 1474-547X</identifier><identifier>PMID: 2870355</identifier><identifier>CODEN: LANCAO</identifier><language>eng</language><publisher>London: Lancet</publisher><subject>Adult ; Anemia - blood ; Anemia - therapy ; Anemia, Neonatal - therapy ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Blood Transfusion ; Blood Volume ; Body Weight ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Erythrocyte Transfusion ; Erythrocyte Volume ; Hematocrit ; Hemoglobins - analysis ; Humans ; Infant ; Infant, Newborn ; Infant, Premature, Diseases - blood ; Infant, Premature, Diseases - therapy ; Intensive care medicine ; Medical sciences ; Plasma Volume</subject><ispartof>The Lancet (British edition), 1986-04, Vol.1 (8486), p.882-884</ispartof><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8664832$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2870355$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>PHILLIPS, H. M</creatorcontrib><creatorcontrib>HOLLAND, B. M</creatorcontrib><creatorcontrib>ABDEL ABDEL-MOIZ</creatorcontrib><creatorcontrib>SUHEIR FAYED</creatorcontrib><creatorcontrib>JONES, J. G</creatorcontrib><creatorcontrib>TURNER, T. L</creatorcontrib><creatorcontrib>WARDROP, C. A. J</creatorcontrib><creatorcontrib>COCKBURN, F</creatorcontrib><title>Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion</title><title>The Lancet (British edition)</title><addtitle>Lancet</addtitle><description>A new method for the rapid determination of red-blood-cell mass (RCM) in infants needing blood transfusion is described. RCM is estimated from the fall in the baby's fetal haemoglobin level resulting from transfusion of a known mass of adult-haemoglobin-containing red cells. In severe blood loss and refractory anaemias in preterm infants, in addition to the red-cell deficit, the plasma volume is low, leading to a falsely high haematocrit of about 0.30, which conceals a deficiency of 50-70% in circulating red cells. Red-cell transfusion in such infants based on haematocrit often fails to restore RCM to normal, leading to repeated transfusions. The frequency of transfusions may be reduced by giving enough red cells fully to correct the deficiency based on RCM estimation.</description><subject>Adult</subject><subject>Anemia - blood</subject><subject>Anemia - therapy</subject><subject>Anemia, Neonatal - therapy</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Blood Transfusion</subject><subject>Blood Volume</subject><subject>Body Weight</subject><subject>Emergency and intensive care: neonates and children. Prematurity. Sudden death</subject><subject>Erythrocyte Transfusion</subject><subject>Erythrocyte Volume</subject><subject>Hematocrit</subject><subject>Hemoglobins - analysis</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infant, Premature, Diseases - blood</subject><subject>Infant, Premature, Diseases - therapy</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Plasma Volume</subject><issn>0140-6736</issn><issn>1474-547X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kE9LxDAQxYMo67r6EYQcxFshbZNJc5T1Lyx4UfBWJs10ydKma9Me_PZGLZ4eb-bHY96csHUutcyU1B-nbC1yKTLQJZyzixgPQggJQq3Yqqi0KJVas8M9TTT2PuDkh8CHlo_ksoa6jvcYI_eBJ6EYewoTx-DSOOCefm2ik6He4w9n0XqKPBA5H_bcdsPg-DRiiO0cU_glO2uxi3S16Ia9Pz68bZ-z3evTy_Zulx1z0FMmZeGcAWuUhsYqLNL9DSiL2rSgwJbKVapowABQS43RgCSMVDmhcwRUbtjtX-5xHD5nilPd-_jTCAMNc6w1aGV0ZRJ4vYCz7cnVx9H3OH7Vy3PS_mbZY2ywa1OVxsd_rAKQVVmU39r_b8Y</recordid><startdate>19860419</startdate><enddate>19860419</enddate><creator>PHILLIPS, H. M</creator><creator>HOLLAND, B. M</creator><creator>ABDEL ABDEL-MOIZ</creator><creator>SUHEIR FAYED</creator><creator>JONES, J. G</creator><creator>TURNER, T. L</creator><creator>WARDROP, C. A. J</creator><creator>COCKBURN, F</creator><general>Lancet</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>19860419</creationdate><title>Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion</title><author>PHILLIPS, H. M ; HOLLAND, B. M ; ABDEL ABDEL-MOIZ ; SUHEIR FAYED ; JONES, J. G ; TURNER, T. L ; WARDROP, C. A. J ; COCKBURN, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p167t-442dd96b9576cb5a2673c65ba79f656b35d852c6966efec976ae09451eadde6e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adult</topic><topic>Anemia - blood</topic><topic>Anemia - therapy</topic><topic>Anemia, Neonatal - therapy</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Blood Transfusion</topic><topic>Blood Volume</topic><topic>Body Weight</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Erythrocyte Transfusion</topic><topic>Erythrocyte Volume</topic><topic>Hematocrit</topic><topic>Hemoglobins - analysis</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Infant, Premature, Diseases - blood</topic><topic>Infant, Premature, Diseases - therapy</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><topic>Plasma Volume</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>PHILLIPS, H. M</creatorcontrib><creatorcontrib>HOLLAND, B. M</creatorcontrib><creatorcontrib>ABDEL ABDEL-MOIZ</creatorcontrib><creatorcontrib>SUHEIR FAYED</creatorcontrib><creatorcontrib>JONES, J. G</creatorcontrib><creatorcontrib>TURNER, T. L</creatorcontrib><creatorcontrib>WARDROP, C. A. J</creatorcontrib><creatorcontrib>COCKBURN, F</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>PHILLIPS, H. M</au><au>HOLLAND, B. M</au><au>ABDEL ABDEL-MOIZ</au><au>SUHEIR FAYED</au><au>JONES, J. G</au><au>TURNER, T. L</au><au>WARDROP, C. A. J</au><au>COCKBURN, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion</atitle><jtitle>The Lancet (British edition)</jtitle><addtitle>Lancet</addtitle><date>1986-04-19</date><risdate>1986</risdate><volume>1</volume><issue>8486</issue><spage>882</spage><epage>884</epage><pages>882-884</pages><issn>0140-6736</issn><eissn>1474-547X</eissn><coden>LANCAO</coden><abstract>A new method for the rapid determination of red-blood-cell mass (RCM) in infants needing blood transfusion is described. RCM is estimated from the fall in the baby's fetal haemoglobin level resulting from transfusion of a known mass of adult-haemoglobin-containing red cells. In severe blood loss and refractory anaemias in preterm infants, in addition to the red-cell deficit, the plasma volume is low, leading to a falsely high haematocrit of about 0.30, which conceals a deficiency of 50-70% in circulating red cells. Red-cell transfusion in such infants based on haematocrit often fails to restore RCM to normal, leading to repeated transfusions. The frequency of transfusions may be reduced by giving enough red cells fully to correct the deficiency based on RCM estimation.</abstract><cop>London</cop><pub>Lancet</pub><pmid>2870355</pmid><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0140-6736 |
| ispartof | The Lancet (British edition), 1986-04, Vol.1 (8486), p.882-884 |
| issn | 0140-6736 1474-547X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76759789 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Anemia - blood Anemia - therapy Anemia, Neonatal - therapy Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Transfusion Blood Volume Body Weight Emergency and intensive care: neonates and children. Prematurity. Sudden death Erythrocyte Transfusion Erythrocyte Volume Hematocrit Hemoglobins - analysis Humans Infant Infant, Newborn Infant, Premature, Diseases - blood Infant, Premature, Diseases - therapy Intensive care medicine Medical sciences Plasma Volume |
| title | Determination of red-cell mass in assessment and management of anaemia in babies needing blood transfusion |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T07%3A41%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Determination%20of%20red-cell%20mass%20in%20assessment%20and%20management%20of%20anaemia%20in%20babies%20needing%20blood%20transfusion&rft.jtitle=The%20Lancet%20(British%20edition)&rft.au=PHILLIPS,%20H.%20M&rft.date=1986-04-19&rft.volume=1&rft.issue=8486&rft.spage=882&rft.epage=884&rft.pages=882-884&rft.issn=0140-6736&rft.eissn=1474-547X&rft.coden=LANCAO&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E76759789%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76759789&rft_id=info:pmid/2870355&rfr_iscdi=true |