Elicitation of specific cytotoxic T cells by immunization with malaria soluble synthetic polypeptides

We have studied the immunogenicity of Plasmodium falciparum circumsporozoite (CS) protein-derived synthetic polypeptides in mice. These synthetic peptides correspond to the N- and the C-terminal domains 22-125 and 289-390, respectively of the P. falciparum 7G8 isolate CS protein expressed on the spo...

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Veröffentlicht in:	The Journal of immunology (1950) 1994-11, Vol.153 (9), p.4134-4141
Hauptverfasser:	Blum-Tirouvanziam, U, Beghdadi-Rais, C, Roggero, MA, Valmori, D, Bertholet, S, Bron, C, Fasel, N, Corradin, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals H-2 Antigens - immunology Malaria Vaccines - immunology Mice Mice, Inbred BALB C Molecular Sequence Data Peptide Fragments - biosynthesis Peptide Fragments - immunology Plasmodium falciparum Protozoan Proteins - biosynthesis Protozoan Proteins - immunology Recombinant Proteins - biosynthesis T-Lymphocytes, Cytotoxic - immunology Transfection
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