Clonidine-evoked selective P1-purinoceptor antagonism of contraction of guinea-pig urinary bladder

The effect of clonidine on P1- and P2-purinoceptors of guinea-pig urinary bladder was compared to that of alpha, beta-methylene ATP, a selective P2-purinoceptor desensitizer. After, alpha, beta-methylene ATP, 10 microM, vesical contraction produced by ATP was eliminated while that caused by acetylch...

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Veröffentlicht in:	European journal of pharmacology 1986-02, Vol.121 (1), p.119-122
Hauptverfasser:	KATSURAGI, T, KURATOMI, L, FURUKAWA, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Animals Biological and medical sciences Clonidine - pharmacology Electric Stimulation Guinea Pigs In Vitro Techniques Male Medical sciences Muscle Contraction - drug effects Muscle, Smooth - drug effects Pharmacology. Drug treatments Receptors, Neurotransmitter - drug effects Receptors, Purinergic Urinary Bladder - drug effects Urinary Bladder - physiology Urinary system
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