The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure

Repression of a-cell specific gene expression in yeast alpha cells requires MAT alpha 2 and MCM1, as well as two global repressors, SSN6 and TUP1. Previous studies demonstrated that nucleosomes positioned adjacent to the alpha 2/MCM1 operator in alpha cells directly contribute to repression. To inve...

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Veröffentlicht in:	Genes & development 1994-06, Vol.8 (12), p.1400-1410
Hauptverfasser:	Cooper, J P, Roth, S Y, Simpson, R T
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP-Binding Cassette Transporters - genetics DNA, Circular - genetics DNA-Binding Proteins - genetics Fungal Proteins - genetics Gene Expression Regulation, Fungal Glycoproteins Mating Factor Minichromosome Maintenance 1 Protein Models, Genetic Nuclear Proteins Nucleic Acid Conformation Nucleosomes - metabolism Operator Regions, Genetic - genetics Peptides - genetics Promoter Regions, Genetic - genetics Recombinant Fusion Proteins - biosynthesis Repressor Proteins - metabolism Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins Sequence Deletion Transcription Factors - genetics Transcription, Genetic
Online-Zugang:	Volltext
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