Ki-1 large cell anaplastic lymphoma. A clinicopathological study
Ki-1 large cell anaplastic lymphoma is a recently described variant of malignant lymphoma. A retrospective study of 10 cases of Ki-1 lymphoma was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi to document its clinical and morphological features. The morphological features w...
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| Veröffentlicht in: | Journal of the Pakistan Medical Association 1994-07, Vol.44 (7), p.169-171 |
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| container_title | Journal of the Pakistan Medical Association |
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| creator | SAJID MUSHTAQ MALIK, I. A MANZOOR AHMED SAFDAR KHAN, M AMIR HUSSAIN KHAN SHAHID JAMAL MALIK F. A |
| description | Ki-1 large cell anaplastic lymphoma is a recently described variant of malignant lymphoma. A retrospective study of 10 cases of Ki-1 lymphoma was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi to document its clinical and morphological features. The morphological features were evaluated by a study of paraffin embedded sections stained with haematoxylin and eosin stains. Immunohistochemical stains for BER-H2 and leucocyte common antigen (LCA) were performed in all cases. The age of the patients ranged from 2 to 60 years and male to female ratio was 2.3:1. Cervical lymphadenopathy was the most common presentation. Histologically, there was a complete effacement of the lymph node architecture in 8 cases. The Reed-Sternberg like cells were seen in 2 and histiocyte like cells in 7 cases. Immunohistochemically all cases were positive for BER-H2. It is suggested that the possibility of Ki-1 lymphoma should be considered in all cases of lymphoma with pleomorphic morphology. |
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A clinicopathological study</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>SAJID MUSHTAQ ; MALIK, I. A ; MANZOOR AHMED ; SAFDAR KHAN, M ; AMIR HUSSAIN KHAN ; SHAHID JAMAL ; MALIK F. A</creator><creatorcontrib>SAJID MUSHTAQ ; MALIK, I. A ; MANZOOR AHMED ; SAFDAR KHAN, M ; AMIR HUSSAIN KHAN ; SHAHID JAMAL ; MALIK F. A</creatorcontrib><description>Ki-1 large cell anaplastic lymphoma is a recently described variant of malignant lymphoma. A retrospective study of 10 cases of Ki-1 lymphoma was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi to document its clinical and morphological features. The morphological features were evaluated by a study of paraffin embedded sections stained with haematoxylin and eosin stains. Immunohistochemical stains for BER-H2 and leucocyte common antigen (LCA) were performed in all cases. The age of the patients ranged from 2 to 60 years and male to female ratio was 2.3:1. Cervical lymphadenopathy was the most common presentation. Histologically, there was a complete effacement of the lymph node architecture in 8 cases. The Reed-Sternberg like cells were seen in 2 and histiocyte like cells in 7 cases. Immunohistochemically all cases were positive for BER-H2. It is suggested that the possibility of Ki-1 lymphoma should be considered in all cases of lymphoma with pleomorphic morphology.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 7933457</identifier><identifier>CODEN: JJPAD4</identifier><language>eng</language><publisher>Karachi: Pakistan Medical Association</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Child ; Child, Preschool ; Female ; Hematologic and hematopoietic diseases ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymphoma, Large-Cell, Anaplastic - pathology ; Male ; Medical sciences ; Middle Aged ; Retrospective Studies ; Tropical medicine</subject><ispartof>Journal of the Pakistan Medical Association, 1994-07, Vol.44 (7), p.169-171</ispartof><rights>1995 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3361993$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7933457$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAJID MUSHTAQ</creatorcontrib><creatorcontrib>MALIK, I. A</creatorcontrib><creatorcontrib>MANZOOR AHMED</creatorcontrib><creatorcontrib>SAFDAR KHAN, M</creatorcontrib><creatorcontrib>AMIR HUSSAIN KHAN</creatorcontrib><creatorcontrib>SHAHID JAMAL</creatorcontrib><creatorcontrib>MALIK F. A</creatorcontrib><title>Ki-1 large cell anaplastic lymphoma. A clinicopathological study</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>Ki-1 large cell anaplastic lymphoma is a recently described variant of malignant lymphoma. A retrospective study of 10 cases of Ki-1 lymphoma was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi to document its clinical and morphological features. The morphological features were evaluated by a study of paraffin embedded sections stained with haematoxylin and eosin stains. Immunohistochemical stains for BER-H2 and leucocyte common antigen (LCA) were performed in all cases. The age of the patients ranged from 2 to 60 years and male to female ratio was 2.3:1. Cervical lymphadenopathy was the most common presentation. Histologically, there was a complete effacement of the lymph node architecture in 8 cases. The Reed-Sternberg like cells were seen in 2 and histiocyte like cells in 7 cases. Immunohistochemically all cases were positive for BER-H2. It is suggested that the possibility of Ki-1 lymphoma should be considered in all cases of lymphoma with pleomorphic morphology.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymphoma, Large-Cell, Anaplastic - pathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Tropical medicine</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j71OwzAYRT2ASik8ApIHxBb0JY7_NqqKP1GJBeboq-20Rk4c4mTI2xNExHSHc3R17xlZAzDItFbFBblM6QugEBxgRVZSM1ZyuSYPbz7LacD-6KhxIVBssQuYBm9omJruFBu8p1tqgm-9iR0Opxji0RsMNA2jna7IeY0hueslN-Tz6fFj95Lt359fd9t91uUchoxjborSYMElWlBaC66sqBVX0hY5aHkwTAiQHGsJqoR5dM6M4TVIqa01bEPu_nq7Pn6PLg1V49PvYmxdHFMlhSy1YGoWbxZxPDTOVl3vG-ynark889uFY5pf1D22xqd_jTGR61n9AWDLXH4</recordid><startdate>199407</startdate><enddate>199407</enddate><creator>SAJID MUSHTAQ</creator><creator>MALIK, I. 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A</creatorcontrib><creatorcontrib>MANZOOR AHMED</creatorcontrib><creatorcontrib>SAFDAR KHAN, M</creatorcontrib><creatorcontrib>AMIR HUSSAIN KHAN</creatorcontrib><creatorcontrib>SHAHID JAMAL</creatorcontrib><creatorcontrib>MALIK F. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAJID MUSHTAQ</au><au>MALIK, I. A</au><au>MANZOOR AHMED</au><au>SAFDAR KHAN, M</au><au>AMIR HUSSAIN KHAN</au><au>SHAHID JAMAL</au><au>MALIK F. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ki-1 large cell anaplastic lymphoma. A clinicopathological study</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>1994-07</date><risdate>1994</risdate><volume>44</volume><issue>7</issue><spage>169</spage><epage>171</epage><pages>169-171</pages><issn>0030-9982</issn><coden>JJPAD4</coden><abstract>Ki-1 large cell anaplastic lymphoma is a recently described variant of malignant lymphoma. A retrospective study of 10 cases of Ki-1 lymphoma was carried out at the Armed Forces Institute of Pathology (AFIP) Rawalpindi to document its clinical and morphological features. The morphological features were evaluated by a study of paraffin embedded sections stained with haematoxylin and eosin stains. Immunohistochemical stains for BER-H2 and leucocyte common antigen (LCA) were performed in all cases. The age of the patients ranged from 2 to 60 years and male to female ratio was 2.3:1. Cervical lymphadenopathy was the most common presentation. Histologically, there was a complete effacement of the lymph node architecture in 8 cases. The Reed-Sternberg like cells were seen in 2 and histiocyte like cells in 7 cases. Immunohistochemically all cases were positive for BER-H2. It is suggested that the possibility of Ki-1 lymphoma should be considered in all cases of lymphoma with pleomorphic morphology.</abstract><cop>Karachi</cop><pub>Pakistan Medical Association</pub><pmid>7933457</pmid><tpages>3</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adolescent Adult Biological and medical sciences Child Child, Preschool Female Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, Large-Cell, Anaplastic - pathology Male Medical sciences Middle Aged Retrospective Studies Tropical medicine |
| title | Ki-1 large cell anaplastic lymphoma. A clinicopathological study |
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