Modification of testicular cytochrome P-450 after fenitrothion administration

1. 1. The effect of fenitrothion on testicular microsomal system was analyzed and compared to the modifications induced by the drug at the hepatic level. 2. 2. Acute (165 mg/kg, 1 day) and subacute (55 mg/kg, 3 days) administration of fenitrothion caused a significant decrease on testicular cytochro...

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Veröffentlicht in:	General pharmacology 1994-05, Vol.25 (3), p.499-503
Hauptverfasser:	Clos, M.Victoria, Ramoneda, Montserrat, Garcia, Gloria
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - metabolism Animals Biological and medical sciences Cytochrome P-450 Enzyme System - drug effects Fenitrothion - pharmacology Hydroxylation Male Medical sciences Microsomes - drug effects Microsomes - enzymology Pesticides, fertilizers and other agrochemicals toxicology Rats Rats, Sprague-Dawley Testis - drug effects Testis - enzymology Toxicology Xenobiotics - metabolism
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