The role of genomic imprinting in implantation

To outline the possible role of the imprinted genes in early human embryogenesis and implantation. Literature review. Studies examining the issues of genomic imprinting, implantation, gestational trophoblastic diseases, placental gene expression, and trophoblast invasion. Certain genes have been sho...

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Veröffentlicht in:Fertility and sterility 1994-11, Vol.62 (5), p.903-910
Hauptverfasser: Goshen, Ran, Ben-Rafael, Zion, Gonik, Bernard, Lustig, Orit, Tannos, Vasilios, de-Groot, Nathan, Hochberg, Abraham A.
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container_end_page 910
container_issue 5
container_start_page 903
container_title Fertility and sterility
container_volume 62
creator Goshen, Ran
Ben-Rafael, Zion
Gonik, Bernard
Lustig, Orit
Tannos, Vasilios
de-Groot, Nathan
Hochberg, Abraham A.
description To outline the possible role of the imprinted genes in early human embryogenesis and implantation. Literature review. Studies examining the issues of genomic imprinting, implantation, gestational trophoblastic diseases, placental gene expression, and trophoblast invasion. Certain genes have been shown to be expressed either in the embryo or in the uterine decidua before implantation. Some of these have been shown to be parentally imprinted, that is, expressed either from their paternal or maternal origin. The paternally expressed genes are linked to placental proliferation and invasiveness. Clinical and basic data from different disciplines indicate that genomic imprinting may be crucial to the process of implantation.
doi_str_mv 10.1016/S0015-0282(16)57048-4
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source MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Animals
Biological and medical sciences
Birth control
Chorionic Gonadotropin - genetics
Chorionic Gonadotropin, beta Subunit, Human
Dosage Compensation, Genetic
Embryo Implantation - genetics
Female
Genomic Imprinting
Gynecology. Andrology. Obstetrics
Humans
implantation
Insulin-Like Growth Factor II - genetics
Male
Medical sciences
Peptide Fragments - genetics
Sterility. Assisted procreation
trophoblast invasion
title The role of genomic imprinting in implantation
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