Methyl-CCNU and methotrexate therapy in patients with advanced colorectal cancer after failure of 5-fluorouracil chemotherapy

Thirty-six patients with advanced colorectal cancer whose disease progressed during treatment with 5-fluorouracil (5-FU) chemotherapy were treated with methyl-CCNU and methotrexate. Five patients (14%) achieved a partial response (PR), three (8%) showed disease regression less than that required for...

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Veröffentlicht in:	American journal of clinical oncology 1986-02, Vol.9 (1), p.27-30
Hauptverfasser:	ZORZITTO, M. L, MYERS, R, BAZOS, M. J, SHEPHERD, F. A, EVANS, W. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Chemotherapy Colonic Neoplasms - drug therapy Female Fluorouracil - therapeutic use Humans Male Medical sciences Methotrexate - therapeutic use Middle Aged Nitrosourea Compounds - therapeutic use Pharmacology. Drug treatments Rectal Neoplasms - drug therapy Semustine - therapeutic use
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