Ecto‐5'‐nucleotidase (CD73) in multidrug‐resistant cell lines generated by doxorubicin

Cytochemical screening for a panel of enzymes revealed increased 5'nucleotidase (5'NT) expression in 3 of 3 Pglycoprotein 170 (Pgp 170)‐positive multidrug‐resistant (MDR) variants of the murine EL4 T‐lymphoma cell line (EL4/ADM, ER2 and ER13). Electron microscopic localization established...

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Veröffentlicht in:	International journal of cancer 1994-10, Vol.59 (1), p.83-93
Hauptverfasser:	Ujházy, Peter, Klobušická, Margita, Babušíková, Olga, Strausbauch, Paul, Mihich, Enrico, Ehrke1, M. Jane
Format:	Artikel
Sprache:	eng
Schlagworte:	5'-Nucleotidase - antagonists & inhibitors 5'-Nucleotidase - metabolism Adenosine - pharmacology Adenosine Monophosphate - pharmacology Animals ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism Cricetinae Cricetulus Doxorubicin - pharmacology Drug Resistance, Multiple Fluorescent Antibody Technique Humans Mice Microscopy, Electron Tumor Cells, Cultured
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