Molecular biology of the Borrelia, bacteria with linear replicons
Interest in Borrelia increased dramatically after the recent discovery of Lyme disease and the observation that it is caused by a novel member of the genus. Borrelia are spirochaetes, organisms that comprise a separate phylum in the kingdom of eubacteria. They differ from other bacteria in having a...
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Veröffentlicht in: | Microbiology (Society for General Microbiology) 1994-08, Vol.140 (8), p.1803-1816 |
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creator | SAINT GIRONS, I OLD, I. G DAVIDSON, B. E |
description | Interest in Borrelia increased dramatically after the recent discovery of Lyme disease and the observation that it is caused by a novel member of the genus. Borrelia are spirochaetes, organisms that comprise a separate phylum in the kingdom of eubacteria. They differ from other bacteria in having a helical shape with multiple waves and endoflagella. In this review, we concentrate on the molecular biology of the causative agents of Lyme disease and North American relapsing fever (Borrelia burgdorferi sensu lato and Borrelia hermsii, respectively) because they have received the most research attention. To contain the review within reasonable limits we have not attempted to cover the taxonomy of the Borrelia or the widespread literature on antigenic variation of B. hermsii. |
doi_str_mv | 10.1099/13500872-140-8-1803 |
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G ; DAVIDSON, B. E</creator><creatorcontrib>SAINT GIRONS, I ; OLD, I. G ; DAVIDSON, B. E</creatorcontrib><description>Interest in Borrelia increased dramatically after the recent discovery of Lyme disease and the observation that it is caused by a novel member of the genus. Borrelia are spirochaetes, organisms that comprise a separate phylum in the kingdom of eubacteria. They differ from other bacteria in having a helical shape with multiple waves and endoflagella. In this review, we concentrate on the molecular biology of the causative agents of Lyme disease and North American relapsing fever (Borrelia burgdorferi sensu lato and Borrelia hermsii, respectively) because they have received the most research attention. To contain the review within reasonable limits we have not attempted to cover the taxonomy of the Borrelia or the widespread literature on antigenic variation of B. hermsii.</description><identifier>ISSN: 1350-0872</identifier><identifier>EISSN: 1465-2080</identifier><identifier>DOI: 10.1099/13500872-140-8-1803</identifier><identifier>PMID: 7921235</identifier><language>eng</language><publisher>Reading: Society for General Microbiology</publisher><subject>Amino Acid Sequence ; Animals ; Bacteriology ; Base Sequence ; Biological and medical sciences ; Borrelia ; Borrelia - genetics ; Borrelia burgdorferi Group - genetics ; Chromosome Mapping ; Chromosomes, Bacterial ; Fundamental and applied biological sciences. Psychology ; Genetics ; Genome, Bacterial ; Humans ; Mice ; Microbiology ; Molecular Sequence Data ; Plasmids ; Replication Origin ; Replicon</subject><ispartof>Microbiology (Society for General Microbiology), 1994-08, Vol.140 (8), p.1803-1816</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c405t-4748f08ed937a8a3d795a7f00abdeb1452eeb95df8e8e75fe52afbda131d4bdc3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4276070$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7921235$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SAINT GIRONS, I</creatorcontrib><creatorcontrib>OLD, I. G</creatorcontrib><creatorcontrib>DAVIDSON, B. E</creatorcontrib><title>Molecular biology of the Borrelia, bacteria with linear replicons</title><title>Microbiology (Society for General Microbiology)</title><addtitle>Microbiology</addtitle><description>Interest in Borrelia increased dramatically after the recent discovery of Lyme disease and the observation that it is caused by a novel member of the genus. Borrelia are spirochaetes, organisms that comprise a separate phylum in the kingdom of eubacteria. They differ from other bacteria in having a helical shape with multiple waves and endoflagella. In this review, we concentrate on the molecular biology of the causative agents of Lyme disease and North American relapsing fever (Borrelia burgdorferi sensu lato and Borrelia hermsii, respectively) because they have received the most research attention. To contain the review within reasonable limits we have not attempted to cover the taxonomy of the Borrelia or the widespread literature on antigenic variation of B. hermsii.</description><subject>Amino Acid Sequence</subject><subject>Animals</subject><subject>Bacteriology</subject><subject>Base Sequence</subject><subject>Biological and medical sciences</subject><subject>Borrelia</subject><subject>Borrelia - genetics</subject><subject>Borrelia burgdorferi Group - genetics</subject><subject>Chromosome Mapping</subject><subject>Chromosomes, Bacterial</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Genetics</subject><subject>Genome, Bacterial</subject><subject>Humans</subject><subject>Mice</subject><subject>Microbiology</subject><subject>Molecular Sequence Data</subject><subject>Plasmids</subject><subject>Replication Origin</subject><subject>Replicon</subject><issn>1350-0872</issn><issn>1465-2080</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMtOwzAQRS0EKs8vQEhZIFYExrEdO0uoeEkgNrC2HGdMjdy62IlQ_55ULWxZzUj33Ls4hJxSuKLQNNeUCQAlq5JyKFVJFbAdckB5LcoKFOyO_0iUa2SfHOb8CTCGQCdkIpuKVkwckJuXGNAOwaSi9THEj1URXdHPsLiNKWHw5rJoje0xeVN8-35WBL_AkU64DN7GRT4me86EjCfbe0Te7-_epo_l8-vD0_TmubQcRF9yyZUDhV3DpFGGdbIRRjoA03bYUi4qxLYRnVOoUAqHojKu7QxltONtZ9kRudjsLlP8GjD3eu6zxRDMAuOQtawlqxVX_4K0rqUUrBlBtgFtijkndHqZ_Nyklaag14b1r2E9GtZKrw2PrbPt_NDOsfvrbJWO-fk2N9ma4JJZWJ__MF7JGiSwH0XrgzA</recordid><startdate>19940801</startdate><enddate>19940801</enddate><creator>SAINT GIRONS, I</creator><creator>OLD, I. 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Psychology</topic><topic>Genetics</topic><topic>Genome, Bacterial</topic><topic>Humans</topic><topic>Mice</topic><topic>Microbiology</topic><topic>Molecular Sequence Data</topic><topic>Plasmids</topic><topic>Replication Origin</topic><topic>Replicon</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SAINT GIRONS, I</creatorcontrib><creatorcontrib>OLD, I. G</creatorcontrib><creatorcontrib>DAVIDSON, B. 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In this review, we concentrate on the molecular biology of the causative agents of Lyme disease and North American relapsing fever (Borrelia burgdorferi sensu lato and Borrelia hermsii, respectively) because they have received the most research attention. To contain the review within reasonable limits we have not attempted to cover the taxonomy of the Borrelia or the widespread literature on antigenic variation of B. hermsii.</abstract><cop>Reading</cop><pub>Society for General Microbiology</pub><pmid>7921235</pmid><doi>10.1099/13500872-140-8-1803</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Amino Acid Sequence Animals Bacteriology Base Sequence Biological and medical sciences Borrelia Borrelia - genetics Borrelia burgdorferi Group - genetics Chromosome Mapping Chromosomes, Bacterial Fundamental and applied biological sciences. Psychology Genetics Genome, Bacterial Humans Mice Microbiology Molecular Sequence Data Plasmids Replication Origin Replicon |
title | Molecular biology of the Borrelia, bacteria with linear replicons |
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