Endoscopic ultrasonography in the staging and follow-up of epidermoid carcinoma of the anal canal
Epidermoid (squamous cell) carcinomas of the anal canal are relatively rare, accounting for less than 3% of all malignant tumors affecting the large intestine. Radiation therapy alone or combined with chemotherapy is the treatment of choice. To be effective, this requires initially correct staging a...
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| Veröffentlicht in: | Gastrointestinal endoscopy 1994-07, Vol.40 (4), p.447-450 |
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| creator | Roseau, Gilles Palazzo, Laurent Colardelle, Philippe Chaussade, Stanislas Couturier, Daniel Paolaggi, Joseph Antoine |
| description | Epidermoid (squamous cell) carcinomas of the anal canal are relatively rare, accounting for less than 3% of all malignant tumors affecting the large intestine. Radiation therapy alone or combined with chemotherapy is the treatment of choice. To be effective, this requires initially correct staging and accurate follow-up. Endoscopic ultrasonography plays an essential role, which, during a period of 20 months, we applied to 20 patients. This made possible initial staging according to the TNM classification system. Follow-up examinations showed reduction in size of lesions in all cases. Three patients required early post-radiation surgical intervention because of rectal or vaginal invasion or lymph node metastases. Recurrence in 3 patients, evident by mural expansion on consecutive ultrasound examinations, was diagnosed at 6, 10, and 12 months. In all 6 patients requiring surgical intervention, good correlation was observed between ultrasonic images and operative findings. (Gastrointest Endosc 1994;40:447-50) |
| doi_str_mv | 10.1016/S0016-5107(94)70207-1 |
| format | Article |
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Radiation therapy alone or combined with chemotherapy is the treatment of choice. To be effective, this requires initially correct staging and accurate follow-up. Endoscopic ultrasonography plays an essential role, which, during a period of 20 months, we applied to 20 patients. This made possible initial staging according to the TNM classification system. Follow-up examinations showed reduction in size of lesions in all cases. Three patients required early post-radiation surgical intervention because of rectal or vaginal invasion or lymph node metastases. Recurrence in 3 patients, evident by mural expansion on consecutive ultrasound examinations, was diagnosed at 6, 10, and 12 months. In all 6 patients requiring surgical intervention, good correlation was observed between ultrasonic images and operative findings. 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Radiation therapy alone or combined with chemotherapy is the treatment of choice. To be effective, this requires initially correct staging and accurate follow-up. Endoscopic ultrasonography plays an essential role, which, during a period of 20 months, we applied to 20 patients. This made possible initial staging according to the TNM classification system. Follow-up examinations showed reduction in size of lesions in all cases. Three patients required early post-radiation surgical intervention because of rectal or vaginal invasion or lymph node metastases. Recurrence in 3 patients, evident by mural expansion on consecutive ultrasound examinations, was diagnosed at 6, 10, and 12 months. In all 6 patients requiring surgical intervention, good correlation was observed between ultrasonic images and operative findings. (Gastrointest Endosc 1994;40:447-50)</description><subject>Aged</subject><subject>Anus Neoplasms - diagnostic imaging</subject><subject>Anus Neoplasms - therapy</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - diagnostic imaging</subject><subject>Carcinoma, Squamous Cell - therapy</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Proctoscopy</subject><subject>Prospective Studies</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Proctoscopy</topic><topic>Prospective Studies</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><topic>Tumors</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roseau, Gilles</creatorcontrib><creatorcontrib>Palazzo, Laurent</creatorcontrib><creatorcontrib>Colardelle, Philippe</creatorcontrib><creatorcontrib>Chaussade, Stanislas</creatorcontrib><creatorcontrib>Couturier, Daniel</creatorcontrib><creatorcontrib>Paolaggi, Joseph Antoine</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Gastrointestinal endoscopy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roseau, Gilles</au><au>Palazzo, Laurent</au><au>Colardelle, Philippe</au><au>Chaussade, Stanislas</au><au>Couturier, Daniel</au><au>Paolaggi, Joseph Antoine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endoscopic ultrasonography in the staging and follow-up of epidermoid carcinoma of the anal canal</atitle><jtitle>Gastrointestinal endoscopy</jtitle><addtitle>Gastrointest Endosc</addtitle><date>1994-07-01</date><risdate>1994</risdate><volume>40</volume><issue>4</issue><spage>447</spage><epage>450</epage><pages>447-450</pages><issn>0016-5107</issn><eissn>1097-6779</eissn><coden>GAENBQ</coden><abstract>Epidermoid (squamous cell) carcinomas of the anal canal are relatively rare, accounting for less than 3% of all malignant tumors affecting the large intestine. Radiation therapy alone or combined with chemotherapy is the treatment of choice. To be effective, this requires initially correct staging and accurate follow-up. Endoscopic ultrasonography plays an essential role, which, during a period of 20 months, we applied to 20 patients. This made possible initial staging according to the TNM classification system. Follow-up examinations showed reduction in size of lesions in all cases. Three patients required early post-radiation surgical intervention because of rectal or vaginal invasion or lymph node metastases. Recurrence in 3 patients, evident by mural expansion on consecutive ultrasound examinations, was diagnosed at 6, 10, and 12 months. In all 6 patients requiring surgical intervention, good correlation was observed between ultrasonic images and operative findings. 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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aged Anus Neoplasms - diagnostic imaging Anus Neoplasms - therapy Biological and medical sciences Carcinoma, Squamous Cell - diagnostic imaging Carcinoma, Squamous Cell - therapy Female Follow-Up Studies Gastroenterology. Liver. Pancreas. Abdomen Humans Male Medical sciences Middle Aged Proctoscopy Prospective Studies Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Ultrasonography |
| title | Endoscopic ultrasonography in the staging and follow-up of epidermoid carcinoma of the anal canal |
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