Protection by the Calcium Antagonist Tiapamil, Against Cardiac Lymphatic Enzyme Leakage and Arrhythmias in Canine Hearts During Reperfusion

We examined the effects of tiapamil, a Ca antagonist, on infarct size, lymphatic enzyme release, and arrhythmias in reperfused, ischemic canine hearts. Three-hour reperfusion of the left anterior descending coronary artery, which had been ligated for 3 h, significantly increased cardiac lymphatic re...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 1986-01, Vol.8 (1), p.90-98
Hauptverfasser:	Matsuura, Akihiro, Ishihara, Takafumi, Nakamura, Kazuo, Himori, Norio, Nakamura, Keiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiarythmic agents Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - prevention & control Biological and medical sciences Calcium Channel Blockers - pharmacology Cardiovascular system Cathepsin D - metabolism Coronary Disease - drug therapy Coronary Disease - physiopathology Creatine Kinase - metabolism Dogs Female L-Lactate Dehydrogenase - metabolism Lymphatic System - drug effects Lymphatic System - enzymology Male Medical sciences Myocardial Infarction - drug therapy Myocardial Infarction - pathology Myocardial Infarction - physiopathology Pharmacology. Drug treatments Propylamines - administration & dosage Propylamines - pharmacology Tiapamil Hydrochloride Time Factors
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