Antigen-antibody recognition. Model calculations

Free energy of antigen-antibody binding has been calculated for HyHEL-5, HyHEL-10, and D1.3 complexes. We also have calculated free energies of binding per residue of L- and H- chains of the antibodies, and those of the antigen (lysozyme). The results of the calculations provide support for the noti...

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Veröffentlicht in:	Biophysical chemistry 1994-08, Vol.51 (2), p.337-347
Hauptverfasser:	Nauchitel, Vladimir V., Somorjai, Rajmund L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Accessibility Amino Acid Sequence Amino Acids - chemistry Animals Antibody Antigen Antigen-Antibody Complex - chemistry Binding Sites Chemical Phenomena Chemistry, Physical Hydrophobicity Immunoglobulin Fab Fragments - chemistry Models, Chemical Molecular Sequence Data Muramidase - chemistry Muramidase - immunology Proteins Recognition Residues Thermodynamics
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