Cysteamine, zinc, and thiols modify detectability of rat pituitary prolactin: A comparison with effects on bovine prolactin suggests differences in hormone storage

Little is known about the structure of prolactin (PRL) within secretory granules. Evidence from our previous studies in bovine tissue preparations suggests that control of secretion may reside, in part, in the conversion of storage hormone to releasable PRL. The conversion can be monitored by measur...

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Veröffentlicht in:	Metab., Clin. Exp.; (United States) Clin. Exp.; (United States), 1986-03, Vol.35 (3), p.209-215
Hauptverfasser:	Jacobs, Laurence S., Lorenson, Mary Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	550601 - Medicine- Unsealed Radionuclides in Diagnostics 560305 - Chemicals Metabolism & Toxicology- Vertebrates- (-1987) AMIDES AMINES AMINO ACIDS ANIMALS Biological and medical sciences BIOLOGICAL EFFECTS CARBONIC ACID DERIVATIVES CARBOXYLIC ACIDS CATTLE CHELATING AGENTS Chromatography, High Pressure Liquid Cysteamine - pharmacology Cytoplasmic Granules - analysis DOMESTIC ANIMALS DRUGS Edetic Acid - pharmacology EDTA ELEMENTS Fundamental and applied biological sciences. Psychology GLUTATHIONE Glutathione - pharmacology GONADOTROPINS HORMONES Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis IMMUNOASSAY IMMUNOLOGY ISOTOPE APPLICATIONS LACTATION LTH Male MAMMALS MEA METALS ORGANIC ACIDS ORGANIC COMPOUNDS ORGANIC NITROGEN COMPOUNDS ORGANIC SULFUR COMPOUNDS PEPTIDE HORMONES PEPTIDES Pituitary Gland, Anterior - analysis PITUITARY HORMONES POLYPEPTIDES Prolactin - analysis PROTEINS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOASSAY RADIOIMMUNOASSAY RADIOIMMUNOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOPROTECTIVE SUBSTANCES RATS RODENTS RUMINANTS SECRETION Sodium Dodecyl Sulfate - pharmacology Species Specificity Sulfhydryl Compounds - pharmacology Temperature THIOLS Time Factors TRACER TECHNIQUES UREA Urea - pharmacology VERTEBRATES Vertebrates: endocrinology ZINC Zinc - pharmacology
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