A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant
A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in...
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Veröffentlicht in: | Internal Medicine 1994, Vol.33(6), pp.373-375 |
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creator | KURITA, Akira HASUNUMA, Takeo MOCHI, Soichiro SHIMADA, Takao ISOGAI, Yukihide KURAHASHI, Tomoko |
description | A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in addition to the neurological deficits. Neuroradiological examinations revealed multiple brain infarcts. He had no risk factor for stroke except for lupus anticoagulant. He was diagnosed as having multi-infarct dementia associated with antiphospholipid antibodies. This case suggests that it is necessary to investigate antiphospholipid antibodies in addition to neuroradiological examination when relatively young patients present with unexplained cognitive or behavioral symptoms. (Internal Medicine 33: 373-375, 1994) |
doi_str_mv | 10.2169/internalmedicine.33.373 |
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During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in addition to the neurological deficits. Neuroradiological examinations revealed multiple brain infarcts. He had no risk factor for stroke except for lupus anticoagulant. He was diagnosed as having multi-infarct dementia associated with antiphospholipid antibodies. This case suggests that it is necessary to investigate antiphospholipid antibodies in addition to neuroradiological examination when relatively young patients present with unexplained cognitive or behavioral symptoms. (Internal Medicine 33: 373-375, 1994)</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.33.373</identifier><identifier>PMID: 7919628</identifier><language>eng</language><publisher>Tokyo: The Japanese Society of Internal Medicine</publisher><subject>Adult ; Antibodies, Anticardiolipin - blood ; antiphospholipid antibodies ; Biological and medical sciences ; brain infarction ; Cognition Disorders - etiology ; Dementia, Multi-Infarct - etiology ; Dementia, Multi-Infarct - psychology ; Electroencephalography ; Humans ; Lupus Coagulation Inhibitor - blood ; Male ; Medical sciences ; Neurology ; Risk Factors ; vascular dementia ; Vascular diseases and vascular malformations of the nervous system</subject><ispartof>Internal Medicine, 1994, Vol.33(6), pp.373-375</ispartof><rights>The Japanese Society of Internal Medicine</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4403-260be18f7cd4cd48bc9aca35b42ba93ce179e2a18022c5e27ff37b18ac4f17163</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,1883,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4265897$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7919628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KURITA, Akira</creatorcontrib><creatorcontrib>HASUNUMA, Takeo</creatorcontrib><creatorcontrib>MOCHI, Soichiro</creatorcontrib><creatorcontrib>SHIMADA, Takao</creatorcontrib><creatorcontrib>ISOGAI, Yukihide</creatorcontrib><creatorcontrib>KURAHASHI, Tomoko</creatorcontrib><title>A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in addition to the neurological deficits. Neuroradiological examinations revealed multiple brain infarcts. He had no risk factor for stroke except for lupus anticoagulant. He was diagnosed as having multi-infarct dementia associated with antiphospholipid antibodies. This case suggests that it is necessary to investigate antiphospholipid antibodies in addition to neuroradiological examination when relatively young patients present with unexplained cognitive or behavioral symptoms. (Internal Medicine 33: 373-375, 1994)</description><subject>Adult</subject><subject>Antibodies, Anticardiolipin - blood</subject><subject>antiphospholipid antibodies</subject><subject>Biological and medical sciences</subject><subject>brain infarction</subject><subject>Cognition Disorders - etiology</subject><subject>Dementia, Multi-Infarct - etiology</subject><subject>Dementia, Multi-Infarct - psychology</subject><subject>Electroencephalography</subject><subject>Humans</subject><subject>Lupus Coagulation Inhibitor - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neurology</subject><subject>Risk Factors</subject><subject>vascular dementia</subject><subject>Vascular diseases and vascular malformations of the nervous system</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkEtr4zAURkWZoU0fP6HUi6E7Zyxd27KWIX1ChplFu-hKXCvXqYojp5LMMP9-VGKyaEFcLb5zHxzGrngxF7xWP62L5B32W1pbYx3NAeYg4YjNOJQqlwKqb2xWKN7kIpUTdhrCW1FAI5U4ZsdScVWLZsZWi-xlGN0mW2Kg7K-Nr9mvsY82f3QdehOzG9qSixazRQiDsRhpvcdW424M2SJlZsDN2KOL5-x7h32gi-k_Y893t0_Lh3z1-_5xuVjlpiwLyEVdtMSbTpp1mV7TGoUGoWpL0aICQ1wqEsibQghTkZBdB7LlDZqy45LXcMau93N3fngfKUS9tcFQn26gYQxa1lIIBVUC5R40fgjBU6d33m7R_9O80B8e9WePGkAnj6nzcloxtik79E3iUv5jyjEY7DuPzthwwEpRV42SCfuzx95CxA0dcvRJW09f1nOlxMcJ9VQkHFDzil6Tg_86BZ47</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>KURITA, Akira</creator><creator>HASUNUMA, Takeo</creator><creator>MOCHI, Soichiro</creator><creator>SHIMADA, Takao</creator><creator>ISOGAI, Yukihide</creator><creator>KURAHASHI, Tomoko</creator><general>The Japanese Society of Internal Medicine</general><general>Japanese Society of Internal Medicine</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant</title><author>KURITA, Akira ; HASUNUMA, Takeo ; MOCHI, Soichiro ; SHIMADA, Takao ; ISOGAI, Yukihide ; KURAHASHI, Tomoko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4403-260be18f7cd4cd48bc9aca35b42ba93ce179e2a18022c5e27ff37b18ac4f17163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Adult</topic><topic>Antibodies, Anticardiolipin - blood</topic><topic>antiphospholipid antibodies</topic><topic>Biological and medical sciences</topic><topic>brain infarction</topic><topic>Cognition Disorders - etiology</topic><topic>Dementia, Multi-Infarct - etiology</topic><topic>Dementia, Multi-Infarct - psychology</topic><topic>Electroencephalography</topic><topic>Humans</topic><topic>Lupus Coagulation Inhibitor - blood</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neurology</topic><topic>Risk Factors</topic><topic>vascular dementia</topic><topic>Vascular diseases and vascular malformations of the nervous system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KURITA, Akira</creatorcontrib><creatorcontrib>HASUNUMA, Takeo</creatorcontrib><creatorcontrib>MOCHI, Soichiro</creatorcontrib><creatorcontrib>SHIMADA, Takao</creatorcontrib><creatorcontrib>ISOGAI, Yukihide</creatorcontrib><creatorcontrib>KURAHASHI, Tomoko</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KURITA, Akira</au><au>HASUNUMA, Takeo</au><au>MOCHI, Soichiro</au><au>SHIMADA, Takao</au><au>ISOGAI, Yukihide</au><au>KURAHASHI, Tomoko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>1994</date><risdate>1994</risdate><volume>33</volume><issue>6</issue><spage>373</spage><epage>375</epage><pages>373-375</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in addition to the neurological deficits. Neuroradiological examinations revealed multiple brain infarcts. He had no risk factor for stroke except for lupus anticoagulant. He was diagnosed as having multi-infarct dementia associated with antiphospholipid antibodies. This case suggests that it is necessary to investigate antiphospholipid antibodies in addition to neuroradiological examination when relatively young patients present with unexplained cognitive or behavioral symptoms. (Internal Medicine 33: 373-375, 1994)</abstract><cop>Tokyo</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>7919628</pmid><doi>10.2169/internalmedicine.33.373</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Antibodies, Anticardiolipin - blood antiphospholipid antibodies Biological and medical sciences brain infarction Cognition Disorders - etiology Dementia, Multi-Infarct - etiology Dementia, Multi-Infarct - psychology Electroencephalography Humans Lupus Coagulation Inhibitor - blood Male Medical sciences Neurology Risk Factors vascular dementia Vascular diseases and vascular malformations of the nervous system |
title | A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant |
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