A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant

A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in...

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Veröffentlicht in:Internal Medicine 1994, Vol.33(6), pp.373-375
Hauptverfasser: KURITA, Akira, HASUNUMA, Takeo, MOCHI, Soichiro, SHIMADA, Takao, ISOGAI, Yukihide, KURAHASHI, Tomoko
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container_end_page 375
container_issue 6
container_start_page 373
container_title Internal Medicine
container_volume 33
creator KURITA, Akira
HASUNUMA, Takeo
MOCHI, Soichiro
SHIMADA, Takao
ISOGAI, Yukihide
KURAHASHI, Tomoko
description A 39-year-old man was admitted because of an abrupt onset of right-side weakness and dysarthria. During the 2 years before admission, he had suffered from insomnia, depressed mood and progressive memory disturbance. Neurological and psychiatric examination revealed severe intellectual impairment in addition to the neurological deficits. Neuroradiological examinations revealed multiple brain infarcts. He had no risk factor for stroke except for lupus anticoagulant. He was diagnosed as having multi-infarct dementia associated with antiphospholipid antibodies. This case suggests that it is necessary to investigate antiphospholipid antibodies in addition to neuroradiological examination when relatively young patients present with unexplained cognitive or behavioral symptoms. (Internal Medicine 33: 373-375, 1994)
doi_str_mv 10.2169/internalmedicine.33.373
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subjects Adult
Antibodies, Anticardiolipin - blood
antiphospholipid antibodies
Biological and medical sciences
brain infarction
Cognition Disorders - etiology
Dementia, Multi-Infarct - etiology
Dementia, Multi-Infarct - psychology
Electroencephalography
Humans
Lupus Coagulation Inhibitor - blood
Male
Medical sciences
Neurology
Risk Factors
vascular dementia
Vascular diseases and vascular malformations of the nervous system
title A Young Case with Multi-Infarct Dementia Associated with Lupus Anticoagulant
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