Attenuation of myocardial stunning by the ACE inhibitor ramiprilat through a signal cascade of bradykinin and prostaglandins but not nitric oxide

Attenuation of myocardial stunning by several angiotensin-converting enzyme (ACE) inhibitors has been demonstrated. However, the signal cascade mediating such protective effect has not been analyzed in detail so far. In a first protocol, we addressed the role of bradykinin and analyzed the effect of...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 1994-09, Vol.90 (3), p.1368-1385
Hauptverfasser:	EHRING, T, BAUMGART, D, KRAJCAR, M, HÜMMELGEN, M, KOMPA, S, HEUSCH, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Biological and medical sciences Bradykinin - physiology Cardiovascular system Coronary Circulation - drug effects Dogs Heart - drug effects Heart - physiopathology Hemodynamics - drug effects Medical sciences Myocardial Stunning - physiopathology Nitric Oxide - physiology Pharmacology. Drug treatments Prostaglandins - physiology Ramipril - analogs & derivatives Ramipril - pharmacology Signal Transduction Vasodilator agents. Cerebral vasodilators
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