Effect of corticotropin-releasing factor antagonist on behavioral and neuroendocrine responses during exposure to defensive burying paradigm in rats

Defensive burying behavior is a coping strategy in rodents in response to an aversive stimulus where fear will facilitate burying and treatment with anxiolytics will result in less burying. To test the hypothesis that endogenous corticotropin-releasing factor (CRF) is involved in the defensive buryi...

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Veröffentlicht in:	Physiology & behavior 1994-07, Vol.56 (1), p.115-120
Hauptverfasser:	Korte, S.M., Korte-Bouws, G.A.H., Bohus, B., Koob, G.F.
Format:	Artikel
Sprache:	eng
Schlagworte:	ACTH Adrenocorticotropic Hormone - blood Animals Anxiety Behavioral psychophysiology Biological and medical sciences Brain - drug effects Brain - physiology Corticosterone Corticosterone - blood Corticotropin-Releasing Hormone - antagonists & inhibitors Corticotropin-Releasing Hormone - pharmacology Corticotropin-Releasing Hormone - physiology Defensive burying Electroshock Fear - drug effects Fear - physiology Fundamental and applied biological sciences. Psychology Hormones and behavior Injections, Intraventricular Male Peptide Fragments - pharmacology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Wistar Receptors, Corticotropin-Releasing Hormone - drug effects Receptors, Corticotropin-Releasing Hormone - physiology Stress α-hel CRF 9–41
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