Thyroid hormone deiodinases in purified primary glial cell cultures

Iodothyronine metabolism was studied in neuroglial cells prepared from neonatal rat cerebri. Astrocytes account for nearly all of the deiodinase activity in mixed glial cell cultures. The predominant pathway is 5-deiodination, which closely resembles the enzyme activity in homogenates of cerebral co...

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Veröffentlicht in:	Brain research 1986-02, Vol.364 (2), p.382-385
Hauptverfasser:	Cavalieri, Ralph R., Gavin, Laurence A., Cole, Ruth, de Vellis, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Applied sciences astrocyte Astrocytes - enzymology Biochemistry and metabolism Biological and medical sciences Cells, Cultured Central nervous system cerebrum deiodinase Exact sciences and technology Fundamental and applied biological sciences. Psychology glial cells Iodide Peroxidase - metabolism iodothyronine neuroglia Neuroglia - enzymology oligodendrocyte Oligodendroglia - enzymology Other techniques and industries Rats Telencephalon thyroid hormones thyroxine Thyroxine - metabolism triiodothyronine Triiodothyronine - metabolism Triiodothyronine - pharmacology Vertebrates: nervous system and sense organs
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