The influence of prolonged clofibrate treatment on the plasma drug concentration and liver NADP-linked enzymes activity

1. 1. The clofibric acid (CPIB) concentration in the rat blood plasma during 14 days of treatment with clofibrate and after cessation of the treatment, was measured and compared with the changes of some NADP-linked dehydrogenases activity. 2. 2. CPIB rapidly accumulates in the plasma during the firs...

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Veröffentlicht in:	General pharmacology 1986, Vol.17 (1), p.117-119
Hauptverfasser:	Żelewski, Mateusz, Świerczyński, Julian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Clofibrate - blood Clofibrate - pharmacology Female Liver - drug effects Liver - enzymology Malate Dehydrogenase - analysis NADP - analysis Oxidoreductases - analysis Pentose Phosphate Pathway Protein Biosynthesis Rats Rats, Inbred Strains
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