Effects of Menatetrenone on the Decrease in Calcium Balance Induced by Vitamin K-Deficient Diet and Sodium Loading in Rats

The effects of menatetrenone (2-methyl-3-tetraprenyl-1,4-naphthoquinone, MK-4) on calcium balance were studied in male Sprague-Dawley rats. Experiment 1: Rats in metabolic cages that were fed a vitamin K-deficient diet and injected daily with latamoxef (100 mg/kg, i.p.) were either treated or untrea...

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Veröffentlicht in:	Japanese Journal of Pharmacology 1994, Vol.65 (1), p.35-44
Hauptverfasser:	Tomiuga, Takashi, Kobayashi, Masatoshi, Nakajima, Yoshikage, Bessho, Motoaki, Katoh, Yoshinori, Hara, Kuniko, Akiyama, Yasuhiro, Nakamura, Tetsuya, Tajima, Tetsuya
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - blood Animals Biological and medical sciences Blood Coagulation - drug effects Calcium - metabolism Calcium balance Calcium excretion (fecal) Calcium transport (intestinal) Diet General and cellular metabolism. Vitamins Hemostatics - pharmacology Intestinal Absorption - drug effects Intestinal Mucosa - metabolism Intestines - drug effects Kidney Function Tests lα,25-Dihydroxyvitamin D3 Male Medical sciences Menatetrenone (Vitamin K2) Pharmacology. Drug treatments Phosphates - blood Rats Rats, Sprague-Dawley Sodium - pharmacology Vitamin K - analogs & derivatives Vitamin K - pharmacology Vitamin K 2 - analogs & derivatives Vitamin K Deficiency - metabolism
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