Solid-phase techniques in blood transfusion serology
For nearly a century, erythrocyte agglutination has persisted as the most widely used method for the demonstration of antigen-antibody reaction in immunohematology. So far, no other system has been developed which can match its simplicity, versatility, and general reliability. The major disadvantage...
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Veröffentlicht in: | CRC critical reviews in clinical laboratory sciences 1986, Vol.22 (4), p.317-432 |
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creator | BECK, M. L PLAPP, F. V SINOR, L. T RACHEL, J. M BLUMBERG, N |
description | For nearly a century, erythrocyte agglutination has persisted as the most widely used method for the demonstration of antigen-antibody reaction in immunohematology. So far, no other system has been developed which can match its simplicity, versatility, and general reliability. The major disadvantage of agglutination reactions is the lack of an objective endpoint, which has severely hindered attempts to automate routine pretransfusion tests. To overcome this problem, we have designed a series of solid-phase assays for ABO and Rh grouping, antibody screening, compatibility, and hepatitis tests. Each of these solid-phase assays shares a common endpoint of red cell adherence, which is easily interpreted visually or spectrophotometrically. Computer interface permits the automatic interpretation and recording of results. We believe this solid-phase system should finally bring the blood bank laboratory into the age of automation. |
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L ; PLAPP, F. V ; SINOR, L. T ; RACHEL, J. M ; BLUMBERG, N</creator><creatorcontrib>BECK, M. L ; PLAPP, F. V ; SINOR, L. T ; RACHEL, J. M ; BLUMBERG, N</creatorcontrib><description>For nearly a century, erythrocyte agglutination has persisted as the most widely used method for the demonstration of antigen-antibody reaction in immunohematology. So far, no other system has been developed which can match its simplicity, versatility, and general reliability. The major disadvantage of agglutination reactions is the lack of an objective endpoint, which has severely hindered attempts to automate routine pretransfusion tests. To overcome this problem, we have designed a series of solid-phase assays for ABO and Rh grouping, antibody screening, compatibility, and hepatitis tests. Each of these solid-phase assays shares a common endpoint of red cell adherence, which is easily interpreted visually or spectrophotometrically. Computer interface permits the automatic interpretation and recording of results. We believe this solid-phase system should finally bring the blood bank laboratory into the age of automation.</description><identifier>ISSN: 0590-8191</identifier><identifier>ISSN: 1040-8363</identifier><identifier>PMID: 3081297</identifier><language>eng</language><publisher>Cleveland, OH: Chemical Rubber Co</publisher><subject>ABO Blood-Group System - immunology ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Antibodies, Anti-Idiotypic - immunology ; Antibodies, Monoclonal ; Biological and medical sciences ; Blood Grouping and Crossmatching - methods ; Blood Platelets - immunology ; Blood Transfusion ; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis ; Hemagglutination Tests - methods ; Hepatitis B Surface Antigens - analysis ; Humans ; Immune Adherence Reaction ; Isoantibodies - analysis ; Medical sciences ; Rh-Hr Blood-Group System - immunology ; Saliva - immunology ; Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><ispartof>CRC critical reviews in clinical laboratory sciences, 1986, Vol.22 (4), p.317-432</ispartof><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8540705$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3081297$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BECK, M. L</creatorcontrib><creatorcontrib>PLAPP, F. V</creatorcontrib><creatorcontrib>SINOR, L. T</creatorcontrib><creatorcontrib>RACHEL, J. M</creatorcontrib><creatorcontrib>BLUMBERG, N</creatorcontrib><title>Solid-phase techniques in blood transfusion serology</title><title>CRC critical reviews in clinical laboratory sciences</title><addtitle>Crit Rev Clin Lab Sci</addtitle><description>For nearly a century, erythrocyte agglutination has persisted as the most widely used method for the demonstration of antigen-antibody reaction in immunohematology. So far, no other system has been developed which can match its simplicity, versatility, and general reliability. The major disadvantage of agglutination reactions is the lack of an objective endpoint, which has severely hindered attempts to automate routine pretransfusion tests. To overcome this problem, we have designed a series of solid-phase assays for ABO and Rh grouping, antibody screening, compatibility, and hepatitis tests. Each of these solid-phase assays shares a common endpoint of red cell adherence, which is easily interpreted visually or spectrophotometrically. Computer interface permits the automatic interpretation and recording of results. We believe this solid-phase system should finally bring the blood bank laboratory into the age of automation.</description><subject>ABO Blood-Group System - immunology</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Antibodies, Anti-Idiotypic - immunology</subject><subject>Antibodies, Monoclonal</subject><subject>Biological and medical sciences</subject><subject>Blood Grouping and Crossmatching - methods</subject><subject>Blood Platelets - immunology</subject><subject>Blood Transfusion</subject><subject>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</subject><subject>Hemagglutination Tests - methods</subject><subject>Hepatitis B Surface Antigens - analysis</subject><subject>Humans</subject><subject>Immune Adherence Reaction</subject><subject>Isoantibodies - analysis</subject><subject>Medical sciences</subject><subject>Rh-Hr Blood-Group System - immunology</subject><subject>Saliva - immunology</subject><subject>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</subject><issn>0590-8191</issn><issn>1040-8363</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j81KxDAYRbNQxnH0EYQuxF0hP02-ZimDfzDgQl2XJP3iRNKmNu1i3t6KxdVdnMPl3jOypVLTsmaaXZDLnL8oFQKg2pCNoDXjGrakeksxtOVwNBmLCd2xD98z5iL0hY0ptcU0mj77OYfUFxnHFNPn6YqcexMzXq-5Ix-PD-_75_Lw-vSyvz-UA1MwlZYzpzh4kMIq6oTTVgmOmtYewCusTcs5qtY7FFaCp8is5hViWwNXjoodufvrHcb0u2pqupAdxmh6THNuQAHVlWSLeLOKs-2wbYYxdGY8NevNhd-u3GRnol8-uZD_tVpWFKgUP_hUWiw</recordid><startdate>1986</startdate><enddate>1986</enddate><creator>BECK, M. L</creator><creator>PLAPP, F. V</creator><creator>SINOR, L. T</creator><creator>RACHEL, J. M</creator><creator>BLUMBERG, N</creator><general>Chemical Rubber Co</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1986</creationdate><title>Solid-phase techniques in blood transfusion serology</title><author>BECK, M. L ; PLAPP, F. V ; SINOR, L. T ; RACHEL, J. M ; BLUMBERG, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p167t-b21c627f753b60c3c9b632e908f77f6e8ad22e6dfce3b57f0e1b924eed8726c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>ABO Blood-Group System - immunology</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Antibodies, Anti-Idiotypic - immunology</topic><topic>Antibodies, Monoclonal</topic><topic>Biological and medical sciences</topic><topic>Blood Grouping and Crossmatching - methods</topic><topic>Blood Platelets - immunology</topic><topic>Blood Transfusion</topic><topic>Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis</topic><topic>Hemagglutination Tests - methods</topic><topic>Hepatitis B Surface Antigens - analysis</topic><topic>Humans</topic><topic>Immune Adherence Reaction</topic><topic>Isoantibodies - analysis</topic><topic>Medical sciences</topic><topic>Rh-Hr Blood-Group System - immunology</topic><topic>Saliva - immunology</topic><topic>Transfusions. Complications. Transfusion reactions. Cell and gene therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BECK, M. L</creatorcontrib><creatorcontrib>PLAPP, F. V</creatorcontrib><creatorcontrib>SINOR, L. T</creatorcontrib><creatorcontrib>RACHEL, J. M</creatorcontrib><creatorcontrib>BLUMBERG, N</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>CRC critical reviews in clinical laboratory sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BECK, M. L</au><au>PLAPP, F. V</au><au>SINOR, L. T</au><au>RACHEL, J. M</au><au>BLUMBERG, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Solid-phase techniques in blood transfusion serology</atitle><jtitle>CRC critical reviews in clinical laboratory sciences</jtitle><addtitle>Crit Rev Clin Lab Sci</addtitle><date>1986</date><risdate>1986</risdate><volume>22</volume><issue>4</issue><spage>317</spage><epage>432</epage><pages>317-432</pages><issn>0590-8191</issn><issn>1040-8363</issn><abstract>For nearly a century, erythrocyte agglutination has persisted as the most widely used method for the demonstration of antigen-antibody reaction in immunohematology. So far, no other system has been developed which can match its simplicity, versatility, and general reliability. The major disadvantage of agglutination reactions is the lack of an objective endpoint, which has severely hindered attempts to automate routine pretransfusion tests. To overcome this problem, we have designed a series of solid-phase assays for ABO and Rh grouping, antibody screening, compatibility, and hepatitis tests. Each of these solid-phase assays shares a common endpoint of red cell adherence, which is easily interpreted visually or spectrophotometrically. Computer interface permits the automatic interpretation and recording of results. We believe this solid-phase system should finally bring the blood bank laboratory into the age of automation.</abstract><cop>Cleveland, OH</cop><pub>Chemical Rubber Co</pub><pmid>3081297</pmid><tpages>116</tpages></addata></record> |
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subjects | ABO Blood-Group System - immunology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Antibodies, Anti-Idiotypic - immunology Antibodies, Monoclonal Biological and medical sciences Blood Grouping and Crossmatching - methods Blood Platelets - immunology Blood Transfusion Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Hemagglutination Tests - methods Hepatitis B Surface Antigens - analysis Humans Immune Adherence Reaction Isoantibodies - analysis Medical sciences Rh-Hr Blood-Group System - immunology Saliva - immunology Transfusions. Complications. Transfusion reactions. Cell and gene therapy |
title | Solid-phase techniques in blood transfusion serology |
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