Epithelial regulation of prolactin effect on amnionic permeability
The permeability of human amnion to tritiated water is reduced in the presence of both human and ovine prolactin. The cellular composition of amnion is such that the action of prolactin on this membrane probably occurs by way of the epithelium lining the fetal surface. The present study sought to co...
Gespeichert in:
| Veröffentlicht in: | American journal of obstetrics and gynecology 1986-01, Vol.154 (1), p.130-134 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 134 |
|---|---|
| container_issue | 1 |
| container_start_page | 130 |
| container_title | American journal of obstetrics and gynecology |
| container_volume | 154 |
| creator | Raabe, Michael A. McCoshen, John A. |
| description | The permeability of human amnion to tritiated water is reduced in the presence of both human and ovine prolactin. The cellular composition of amnion is such that the action of prolactin on this membrane probably occurs by way of the epithelium lining the fetal surface. The present study sought to confirm an epithelial site of action of prolactin on the permeability of amnionic membrane to tritiated water. In addition, radioautography and competition experiments were conducted to determine a possible receptor-mediated mechanism for prolactin action. Membrane permeability to tritiated water was found to be equivalent for both intact membranes and membranes enzymatically stripped of the lining epithelial cells. However, when ovine prolactin was presented to the fetal surface of amnion, only intact membrane displayed decreased permeability to tritiated water. Although localization of iodine 125-labeled prolactin to the light cell population of amniotic epithelium was observed, positive evidence of a receptor-mediated mechanism could not be established. The results indicate that the permeability of human amnion to water is influenced principally by cells of the epithelium in response to prolactin. |
| doi_str_mv | 10.1016/0002-9378(86)90408-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76704019</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>0002937886904084</els_id><sourcerecordid>76704019</sourcerecordid><originalsourceid>FETCH-LOGICAL-c367t-cc41f426ac4bab60d952e0b1416104282e1f49626b0ff1da87978171be100ca73</originalsourceid><addsrcrecordid>eNp9kM1KxDAURoMo4zj6BgpdiOiimrRpkm4ElfEHBtzoOqTpjUbSdkxaYd7e1CmzdBVuvnMvHwehU4KvCSbsBmOcpWXOxaVgVyWmWKR0D80JLnnKBBP7aL5DDtFRCF_jmJXZDM1yjGlGijm6X65t_wnOKpd4-Bic6m3XJp1J1r5zSve2TcAY0H0Sv1XTxtTqZA2-AVVZZ_vNMTowygU4md4Fen9cvj08p6vXp5eHu1Wqc8b7VGtKDM2Y0rRSFcN1WWSAK0IJI7GMyCDGJctYhY0htRK85IJwUgHBWCueL9DF9m5s9j1A6GVjgwbnVAvdECRnPEogZQTpFtS-C8GDkWtvG-U3kmA5qpOjCDl6kYLJP3WSxrWz6f5QNVDvliZXMT-fchW0csarVtuwwwQvWMHyiN1uMYgufix4GbSFVkNtfdQo687-3-MXPmaJZg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76704019</pqid></control><display><type>article</type><title>Epithelial regulation of prolactin effect on amnionic permeability</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Raabe, Michael A. ; McCoshen, John A.</creator><creatorcontrib>Raabe, Michael A. ; McCoshen, John A.</creatorcontrib><description>The permeability of human amnion to tritiated water is reduced in the presence of both human and ovine prolactin. The cellular composition of amnion is such that the action of prolactin on this membrane probably occurs by way of the epithelium lining the fetal surface. The present study sought to confirm an epithelial site of action of prolactin on the permeability of amnionic membrane to tritiated water. In addition, radioautography and competition experiments were conducted to determine a possible receptor-mediated mechanism for prolactin action. Membrane permeability to tritiated water was found to be equivalent for both intact membranes and membranes enzymatically stripped of the lining epithelial cells. However, when ovine prolactin was presented to the fetal surface of amnion, only intact membrane displayed decreased permeability to tritiated water. Although localization of iodine 125-labeled prolactin to the light cell population of amniotic epithelium was observed, positive evidence of a receptor-mediated mechanism could not be established. The results indicate that the permeability of human amnion to water is influenced principally by cells of the epithelium in response to prolactin.</description><identifier>ISSN: 0002-9378</identifier><identifier>EISSN: 1097-6868</identifier><identifier>DOI: 10.1016/0002-9378(86)90408-4</identifier><identifier>PMID: 3004215</identifier><identifier>CODEN: AJOGAH</identifier><language>eng</language><publisher>Philadelphia, PA: Elsevier Inc</publisher><subject>Amnion ; Autoradiography ; Biological and medical sciences ; Body Water - metabolism ; epithelium ; Epithelium - metabolism ; Extraembryonic Membranes - drug effects ; Extraembryonic Membranes - metabolism ; Female ; Fundamental and applied biological sciences. Psychology ; Hormone metabolism and regulation ; Humans ; In Vitro Techniques ; Magnesium - pharmacology ; Magnesium Chloride ; Maternal-Fetal Exchange ; Pregnancy ; Pregnancy. Parturition. Lactation ; prolactin ; Prolactin - metabolism ; Receptors, Cell Surface - metabolism ; Trypsin ; Vertebrates: reproduction</subject><ispartof>American journal of obstetrics and gynecology, 1986-01, Vol.154 (1), p.130-134</ispartof><rights>1986</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c367t-cc41f426ac4bab60d952e0b1416104282e1f49626b0ff1da87978171be100ca73</citedby><cites>FETCH-LOGICAL-c367t-cc41f426ac4bab60d952e0b1416104282e1f49626b0ff1da87978171be100ca73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0002-9378(86)90408-4$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,781,785,3551,4025,27927,27928,27929,45999</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8756563$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3004215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Raabe, Michael A.</creatorcontrib><creatorcontrib>McCoshen, John A.</creatorcontrib><title>Epithelial regulation of prolactin effect on amnionic permeability</title><title>American journal of obstetrics and gynecology</title><addtitle>Am J Obstet Gynecol</addtitle><description>The permeability of human amnion to tritiated water is reduced in the presence of both human and ovine prolactin. The cellular composition of amnion is such that the action of prolactin on this membrane probably occurs by way of the epithelium lining the fetal surface. The present study sought to confirm an epithelial site of action of prolactin on the permeability of amnionic membrane to tritiated water. In addition, radioautography and competition experiments were conducted to determine a possible receptor-mediated mechanism for prolactin action. Membrane permeability to tritiated water was found to be equivalent for both intact membranes and membranes enzymatically stripped of the lining epithelial cells. However, when ovine prolactin was presented to the fetal surface of amnion, only intact membrane displayed decreased permeability to tritiated water. Although localization of iodine 125-labeled prolactin to the light cell population of amniotic epithelium was observed, positive evidence of a receptor-mediated mechanism could not be established. The results indicate that the permeability of human amnion to water is influenced principally by cells of the epithelium in response to prolactin.</description><subject>Amnion</subject><subject>Autoradiography</subject><subject>Biological and medical sciences</subject><subject>Body Water - metabolism</subject><subject>epithelium</subject><subject>Epithelium - metabolism</subject><subject>Extraembryonic Membranes - drug effects</subject><subject>Extraembryonic Membranes - metabolism</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hormone metabolism and regulation</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Magnesium - pharmacology</subject><subject>Magnesium Chloride</subject><subject>Maternal-Fetal Exchange</subject><subject>Pregnancy</subject><subject>Pregnancy. Parturition. Lactation</subject><subject>prolactin</subject><subject>Prolactin - metabolism</subject><subject>Receptors, Cell Surface - metabolism</subject><subject>Trypsin</subject><subject>Vertebrates: reproduction</subject><issn>0002-9378</issn><issn>1097-6868</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KxDAURoMo4zj6BgpdiOiimrRpkm4ElfEHBtzoOqTpjUbSdkxaYd7e1CmzdBVuvnMvHwehU4KvCSbsBmOcpWXOxaVgVyWmWKR0D80JLnnKBBP7aL5DDtFRCF_jmJXZDM1yjGlGijm6X65t_wnOKpd4-Bic6m3XJp1J1r5zSve2TcAY0H0Sv1XTxtTqZA2-AVVZZ_vNMTowygU4md4Fen9cvj08p6vXp5eHu1Wqc8b7VGtKDM2Y0rRSFcN1WWSAK0IJI7GMyCDGJctYhY0htRK85IJwUgHBWCueL9DF9m5s9j1A6GVjgwbnVAvdECRnPEogZQTpFtS-C8GDkWtvG-U3kmA5qpOjCDl6kYLJP3WSxrWz6f5QNVDvliZXMT-fchW0csarVtuwwwQvWMHyiN1uMYgufix4GbSFVkNtfdQo687-3-MXPmaJZg</recordid><startdate>198601</startdate><enddate>198601</enddate><creator>Raabe, Michael A.</creator><creator>McCoshen, John A.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198601</creationdate><title>Epithelial regulation of prolactin effect on amnionic permeability</title><author>Raabe, Michael A. ; McCoshen, John A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c367t-cc41f426ac4bab60d952e0b1416104282e1f49626b0ff1da87978171be100ca73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Amnion</topic><topic>Autoradiography</topic><topic>Biological and medical sciences</topic><topic>Body Water - metabolism</topic><topic>epithelium</topic><topic>Epithelium - metabolism</topic><topic>Extraembryonic Membranes - drug effects</topic><topic>Extraembryonic Membranes - metabolism</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hormone metabolism and regulation</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Magnesium - pharmacology</topic><topic>Magnesium Chloride</topic><topic>Maternal-Fetal Exchange</topic><topic>Pregnancy</topic><topic>Pregnancy. Parturition. Lactation</topic><topic>prolactin</topic><topic>Prolactin - metabolism</topic><topic>Receptors, Cell Surface - metabolism</topic><topic>Trypsin</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Raabe, Michael A.</creatorcontrib><creatorcontrib>McCoshen, John A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of obstetrics and gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Raabe, Michael A.</au><au>McCoshen, John A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Epithelial regulation of prolactin effect on amnionic permeability</atitle><jtitle>American journal of obstetrics and gynecology</jtitle><addtitle>Am J Obstet Gynecol</addtitle><date>1986-01</date><risdate>1986</risdate><volume>154</volume><issue>1</issue><spage>130</spage><epage>134</epage><pages>130-134</pages><issn>0002-9378</issn><eissn>1097-6868</eissn><coden>AJOGAH</coden><abstract>The permeability of human amnion to tritiated water is reduced in the presence of both human and ovine prolactin. The cellular composition of amnion is such that the action of prolactin on this membrane probably occurs by way of the epithelium lining the fetal surface. The present study sought to confirm an epithelial site of action of prolactin on the permeability of amnionic membrane to tritiated water. In addition, radioautography and competition experiments were conducted to determine a possible receptor-mediated mechanism for prolactin action. Membrane permeability to tritiated water was found to be equivalent for both intact membranes and membranes enzymatically stripped of the lining epithelial cells. However, when ovine prolactin was presented to the fetal surface of amnion, only intact membrane displayed decreased permeability to tritiated water. Although localization of iodine 125-labeled prolactin to the light cell population of amniotic epithelium was observed, positive evidence of a receptor-mediated mechanism could not be established. The results indicate that the permeability of human amnion to water is influenced principally by cells of the epithelium in response to prolactin.</abstract><cop>Philadelphia, PA</cop><pub>Elsevier Inc</pub><pmid>3004215</pmid><doi>10.1016/0002-9378(86)90408-4</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0002-9378 |
| ispartof | American journal of obstetrics and gynecology, 1986-01, Vol.154 (1), p.130-134 |
| issn | 0002-9378 1097-6868 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76704019 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Amnion Autoradiography Biological and medical sciences Body Water - metabolism epithelium Epithelium - metabolism Extraembryonic Membranes - drug effects Extraembryonic Membranes - metabolism Female Fundamental and applied biological sciences. Psychology Hormone metabolism and regulation Humans In Vitro Techniques Magnesium - pharmacology Magnesium Chloride Maternal-Fetal Exchange Pregnancy Pregnancy. Parturition. Lactation prolactin Prolactin - metabolism Receptors, Cell Surface - metabolism Trypsin Vertebrates: reproduction |
| title | Epithelial regulation of prolactin effect on amnionic permeability |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-16T14%3A48%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Epithelial%20regulation%20of%20prolactin%20effect%20on%20amnionic%20permeability&rft.jtitle=American%20journal%20of%20obstetrics%20and%20gynecology&rft.au=Raabe,%20Michael%20A.&rft.date=1986-01&rft.volume=154&rft.issue=1&rft.spage=130&rft.epage=134&rft.pages=130-134&rft.issn=0002-9378&rft.eissn=1097-6868&rft.coden=AJOGAH&rft_id=info:doi/10.1016/0002-9378(86)90408-4&rft_dat=%3Cproquest_cross%3E76704019%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76704019&rft_id=info:pmid/3004215&rft_els_id=0002937886904084&rfr_iscdi=true |