Telehygiene System for Preventive Chronopharmacology in Space

A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of clinical pharmacology 1994-06, Vol.34 (6), p.552-557
Hauptverfasser: Halberg, Franz, Cornélissen, Germaine, Bingham, Christopher, del Pozo, Francisco, Arredondo, Maria Teresa, Otsuka, Kuniaki, Quadens, Olga, Breus, Tamara, Rapoport, Semyon, Komarov, Feodor
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 557
container_issue 6
container_start_page 552
container_title Journal of clinical pharmacology
container_volume 34
creator Halberg, Franz
Cornélissen, Germaine
Bingham, Christopher
del Pozo, Francisco
Arredondo, Maria Teresa
Otsuka, Kuniaki
Quadens, Olga
Breus, Tamara
Rapoport, Semyon
Komarov, Feodor
description A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved.
doi_str_mv 10.1002/j.1552-4604.1994.tb02006.x
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76701723</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>76701723</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4386-fa37af581fb8ce126f6d3d2393db93438f7ba15751abbd36e3e1264818406e533</originalsourceid><addsrcrecordid>eNqVkV1r2zAUhsVY6dJ2P2Fgxuid3SPL-vBg0Da0TUvoCu0Y7EbI9lHjzB-plLTxv69NTO4LAgne57wSjwj5TiGiAPHZMqKcx2EiIIlomibROoMYQETbT2Syjz6TCUBKw1gCfCFH3i8BqEg4PSSHChRjik_IryescNE9l9hg8Nj5NdaBbV3w4PAVm3X5isF04dqmXS2Mq03eVu1zF5RN8LgyOZ6QA2sqj1_H_Zj8ub56ms7C-e-b2-nFPMwTpkRoDZPGckVtpnKksbCiYEXMUlZkKesRKzNDueTUZFnBBLIBShRVCQjkjB2T013vyrUvG_RrXZc-x6oyDbYbr6WQQGU8gD93YO5a7x1avXJlbVynKejBnV7qQZAeBOnBnR7d6W0__G28ZZPVWOxHR1l9_mPMjc9NZZ1p8tLvsYQy6FePne-wt7LC7gMP0HfTh9lw7CvCXUXZf8h2X2Hcfy0kk1z_vb_R8_RSpfeX__SMvQOpXpor</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>76701723</pqid></control><display><type>article</type><title>Telehygiene System for Preventive Chronopharmacology in Space</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Halberg, Franz ; Cornélissen, Germaine ; Bingham, Christopher ; del Pozo, Francisco ; Arredondo, Maria Teresa ; Otsuka, Kuniaki ; Quadens, Olga ; Breus, Tamara ; Rapoport, Semyon ; Komarov, Feodor</creator><creatorcontrib>Halberg, Franz ; Cornélissen, Germaine ; Bingham, Christopher ; del Pozo, Francisco ; Arredondo, Maria Teresa ; Otsuka, Kuniaki ; Quadens, Olga ; Breus, Tamara ; Rapoport, Semyon ; Komarov, Feodor</creatorcontrib><description>A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved.</description><identifier>ISSN: 0091-2700</identifier><identifier>EISSN: 1552-4604</identifier><identifier>DOI: 10.1002/j.1552-4604.1994.tb02006.x</identifier><identifier>PMID: 8083385</identifier><identifier>CODEN: JCPCBR</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Aerospace Medicine ; Applied physiology ; Biological and medical sciences ; Human physiology applied to population studies and life conditions. Human ecophysiology ; Humans ; Medical sciences ; Periodicity ; Pharmacology ; Risk Factors ; Space Flight ; Space life sciences ; Telemetry ; Transports. Aerospace. Diving. Altitude</subject><ispartof>Journal of clinical pharmacology, 1994-06, Vol.34 (6), p.552-557</ispartof><rights>1994 American College of Clinical Pharmacology</rights><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4386-fa37af581fb8ce126f6d3d2393db93438f7ba15751abbd36e3e1264818406e533</citedby><cites>FETCH-LOGICAL-c4386-fa37af581fb8ce126f6d3d2393db93438f7ba15751abbd36e3e1264818406e533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fj.1552-4604.1994.tb02006.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fj.1552-4604.1994.tb02006.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,780,784,789,790,1417,23929,23930,25139,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=4130130$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8083385$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Halberg, Franz</creatorcontrib><creatorcontrib>Cornélissen, Germaine</creatorcontrib><creatorcontrib>Bingham, Christopher</creatorcontrib><creatorcontrib>del Pozo, Francisco</creatorcontrib><creatorcontrib>Arredondo, Maria Teresa</creatorcontrib><creatorcontrib>Otsuka, Kuniaki</creatorcontrib><creatorcontrib>Quadens, Olga</creatorcontrib><creatorcontrib>Breus, Tamara</creatorcontrib><creatorcontrib>Rapoport, Semyon</creatorcontrib><creatorcontrib>Komarov, Feodor</creatorcontrib><title>Telehygiene System for Preventive Chronopharmacology in Space</title><title>Journal of clinical pharmacology</title><addtitle>J Clin Pharmacol</addtitle><description>A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved.</description><subject>Aerospace Medicine</subject><subject>Applied physiology</subject><subject>Biological and medical sciences</subject><subject>Human physiology applied to population studies and life conditions. Human ecophysiology</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Periodicity</subject><subject>Pharmacology</subject><subject>Risk Factors</subject><subject>Space Flight</subject><subject>Space life sciences</subject><subject>Telemetry</subject><subject>Transports. Aerospace. Diving. Altitude</subject><issn>0091-2700</issn><issn>1552-4604</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkV1r2zAUhsVY6dJ2P2Fgxuid3SPL-vBg0Da0TUvoCu0Y7EbI9lHjzB-plLTxv69NTO4LAgne57wSjwj5TiGiAPHZMqKcx2EiIIlomibROoMYQETbT2Syjz6TCUBKw1gCfCFH3i8BqEg4PSSHChRjik_IryescNE9l9hg8Nj5NdaBbV3w4PAVm3X5isF04dqmXS2Mq03eVu1zF5RN8LgyOZ6QA2sqj1_H_Zj8ub56ms7C-e-b2-nFPMwTpkRoDZPGckVtpnKksbCiYEXMUlZkKesRKzNDueTUZFnBBLIBShRVCQjkjB2T013vyrUvG_RrXZc-x6oyDbYbr6WQQGU8gD93YO5a7x1avXJlbVynKejBnV7qQZAeBOnBnR7d6W0__G28ZZPVWOxHR1l9_mPMjc9NZZ1p8tLvsYQy6FePne-wt7LC7gMP0HfTh9lw7CvCXUXZf8h2X2Hcfy0kk1z_vb_R8_RSpfeX__SMvQOpXpor</recordid><startdate>199406</startdate><enddate>199406</enddate><creator>Halberg, Franz</creator><creator>Cornélissen, Germaine</creator><creator>Bingham, Christopher</creator><creator>del Pozo, Francisco</creator><creator>Arredondo, Maria Teresa</creator><creator>Otsuka, Kuniaki</creator><creator>Quadens, Olga</creator><creator>Breus, Tamara</creator><creator>Rapoport, Semyon</creator><creator>Komarov, Feodor</creator><general>Blackwell Publishing Ltd</general><general>Sage Science</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199406</creationdate><title>Telehygiene System for Preventive Chronopharmacology in Space</title><author>Halberg, Franz ; Cornélissen, Germaine ; Bingham, Christopher ; del Pozo, Francisco ; Arredondo, Maria Teresa ; Otsuka, Kuniaki ; Quadens, Olga ; Breus, Tamara ; Rapoport, Semyon ; Komarov, Feodor</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4386-fa37af581fb8ce126f6d3d2393db93438f7ba15751abbd36e3e1264818406e533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Aerospace Medicine</topic><topic>Applied physiology</topic><topic>Biological and medical sciences</topic><topic>Human physiology applied to population studies and life conditions. Human ecophysiology</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Periodicity</topic><topic>Pharmacology</topic><topic>Risk Factors</topic><topic>Space Flight</topic><topic>Space life sciences</topic><topic>Telemetry</topic><topic>Transports. Aerospace. Diving. Altitude</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Halberg, Franz</creatorcontrib><creatorcontrib>Cornélissen, Germaine</creatorcontrib><creatorcontrib>Bingham, Christopher</creatorcontrib><creatorcontrib>del Pozo, Francisco</creatorcontrib><creatorcontrib>Arredondo, Maria Teresa</creatorcontrib><creatorcontrib>Otsuka, Kuniaki</creatorcontrib><creatorcontrib>Quadens, Olga</creatorcontrib><creatorcontrib>Breus, Tamara</creatorcontrib><creatorcontrib>Rapoport, Semyon</creatorcontrib><creatorcontrib>Komarov, Feodor</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Halberg, Franz</au><au>Cornélissen, Germaine</au><au>Bingham, Christopher</au><au>del Pozo, Francisco</au><au>Arredondo, Maria Teresa</au><au>Otsuka, Kuniaki</au><au>Quadens, Olga</au><au>Breus, Tamara</au><au>Rapoport, Semyon</au><au>Komarov, Feodor</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Telehygiene System for Preventive Chronopharmacology in Space</atitle><jtitle>Journal of clinical pharmacology</jtitle><addtitle>J Clin Pharmacol</addtitle><date>1994-06</date><risdate>1994</risdate><volume>34</volume><issue>6</issue><spage>552</spage><epage>557</epage><pages>552-557</pages><issn>0091-2700</issn><eissn>1552-4604</eissn><coden>JCPCBR</coden><abstract>A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>8083385</pmid><doi>10.1002/j.1552-4604.1994.tb02006.x</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0091-2700
ispartof Journal of clinical pharmacology, 1994-06, Vol.34 (6), p.552-557
issn 0091-2700
1552-4604
language eng
recordid cdi_proquest_miscellaneous_76701723
source MEDLINE; Wiley Online Library All Journals
subjects Aerospace Medicine
Applied physiology
Biological and medical sciences
Human physiology applied to population studies and life conditions. Human ecophysiology
Humans
Medical sciences
Periodicity
Pharmacology
Risk Factors
Space Flight
Space life sciences
Telemetry
Transports. Aerospace. Diving. Altitude
title Telehygiene System for Preventive Chronopharmacology in Space
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T23%3A09%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Telehygiene%20System%20for%20Preventive%20Chronopharmacology%20in%20Space&rft.jtitle=Journal%20of%20clinical%20pharmacology&rft.au=Halberg,%20Franz&rft.date=1994-06&rft.volume=34&rft.issue=6&rft.spage=552&rft.epage=557&rft.pages=552-557&rft.issn=0091-2700&rft.eissn=1552-4604&rft.coden=JCPCBR&rft_id=info:doi/10.1002/j.1552-4604.1994.tb02006.x&rft_dat=%3Cproquest_cross%3E76701723%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=76701723&rft_id=info:pmid/8083385&rfr_iscdi=true