A prospective randomized comparison of radiation therapy plus lonidamine versus radiation therapy plus placebo as initial treatment of clinically localized but nonresectable nonsmall cell lung cancer

Purpose : By means of a multicenter, prospective randomized, placebo-controlled study, to assess the impact of adding the radiation-enhancing agent lonidamine to standard “curative-intent” radiation therapy upon overall survival, progression-free survival, and local progression-free survival of pati...

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Veröffentlicht in:	International Journal of Radiation Oncology, Biology and Physics Biology and Physics, 1994-07, Vol.29 (5), p.999-1004
Hauptverfasser:	Scarantino, Charles W., McCunniff, Ann J., Evans, Greg, Young, Charles W., Paggiarino, Dario A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents - therapeutic use Biological and medical sciences BIOLOGY AND MEDICINE, APPLIED STUDIES Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - radiotherapy Carcinoma, Non-Small-Cell Lung - surgery Combined Modality Therapy Combined treatments (chemotherapy of immunotherapy associated with an other treatment) Double-Blind Method Humans Indazoles - therapeutic use Lonidamine Lung Neoplasms - drug therapy Lung Neoplasms - radiotherapy Lung Neoplasms - surgery LUNGS Male Medical sciences NEOPLASMS Nonsmall cell lung cancer PERFORMANCE TESTING Pharmacology. Drug treatments Prospective Studies Radiation-enhancement Radiation-Sensitizing Agents - therapeutic use RADIOSENSITIZERS RADIOTHERAPY
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