A prospective randomized double-blind trial of bolus urokinase in the treatment of established Hickman catheter sepsis in children

Background: The incidence of Hickman catheter sepsis is 10% to 40%, with resultant catheter loss in one third of infections. Urokinase causes dissolution of colonized intra-catheter fibrin thrombi and may improve salvage. Study aims: To evaluate the efficacy of 12-hour-interval slow-push urokinase i...

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Veröffentlicht in:	Journal of pediatric surgery 1994-06, Vol.29 (6), p.742-745
Hauptverfasser:	La Quaglia, Michael P., Caldwell, Christopher, Lucas, Alice, Corbally, Martin, Heller, Glenn, Steinherz, Laurel, Brown, Arthur E., Groeger, Jeffrey, Exelby, Philip R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - isolation & purification Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Catheterization, Central Venous - adverse effects Catheters, Indwelling - adverse effects Child Child, Preschool Colony Count, Microbial Double-Blind Method Female Humans Infection - complications Infection - drug therapy Infection - etiology Infection - microbiology Male Medical sciences Neoplasms - therapy Pharmacology. Drug treatments Prospective Studies Thrombosis - complications Thrombosis - drug therapy Urokinase-Type Plasminogen Activator - administration & dosage
Online-Zugang:	Volltext
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