In Vitro Fertilization and Embryo Transfer: Two-Year Experience
Between February 1983 and January 1985, 206 laparoscopies were performed on 172 women following controlled ovarian hyperstimulation with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG). Sixty-four clinical pregnancies advanced beyond the sixth week of gestation and were co...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1986-03, Vol.67 (3), p.309-315 |
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container_title | Obstetrics and gynecology (New York. 1953) |
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creator | SHER, GEOFFREY KNUTZEN, VICTOR STRATTON, CLIFFORD CHOTINER, HAROLD MAYVILLE, JACK |
description | Between February 1983 and January 1985, 206 laparoscopies were performed on 172 women following controlled ovarian hyperstimulation with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG). Sixty-four clinical pregnancies advanced beyond the sixth week of gestation and were confirmed by ultrasound; and 37.2% of the patients conceived after in vitro fertilization and embryo transfer. The clinical pregnancy rate was 31.1% when based on the number of laparoscopies performed and 33.9% when based on the number of embryo transfers. There were 12 multiple pregnancies (18.8%), 11 miscarriages (17.2%), and one ectopic (tubal) pregnancy (1.6%). The most important factors contributing toward the success of this program were the establishment of specific criteria for patient selection, rigid adherence to clinical and laboratory protocols, and the maintenance of strict quality control. |
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Sixty-four clinical pregnancies advanced beyond the sixth week of gestation and were confirmed by ultrasound; and 37.2% of the patients conceived after in vitro fertilization and embryo transfer. The clinical pregnancy rate was 31.1% when based on the number of laparoscopies performed and 33.9% when based on the number of embryo transfers. There were 12 multiple pregnancies (18.8%), 11 miscarriages (17.2%), and one ectopic (tubal) pregnancy (1.6%). The most important factors contributing toward the success of this program were the establishment of specific criteria for patient selection, rigid adherence to clinical and laboratory protocols, and the maintenance of strict quality control.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 2935761</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: The American College of Obstetricians and Gynecologists</publisher><subject>Abortion, Spontaneous - epidemiology ; Adult ; Biological and medical sciences ; Birth control ; Chorionic Gonadotropin - pharmacology ; Embryo Transfer ; Female ; Fertilization in Vitro ; Gynecology. Andrology. Obstetrics ; Humans ; Infant, Newborn ; Infertility, Female - etiology ; Infertility, Female - therapy ; Laparoscopy ; Medical sciences ; Menotropins - pharmacology ; Oocytes ; Ovary - drug effects ; Parity ; Pregnancy ; Pregnancy, Multiple ; Pregnancy, Tubal - epidemiology ; Quality Control ; Sterility. Assisted procreation ; Ultrasonography</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1986-03, Vol.67 (3), p.309-315</ispartof><rights>1986 The American College of Obstetricians and Gynecologists</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8735027$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2935761$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SHER, GEOFFREY</creatorcontrib><creatorcontrib>KNUTZEN, VICTOR</creatorcontrib><creatorcontrib>STRATTON, CLIFFORD</creatorcontrib><creatorcontrib>CHOTINER, HAROLD</creatorcontrib><creatorcontrib>MAYVILLE, JACK</creatorcontrib><title>In Vitro Fertilization and Embryo Transfer: Two-Year Experience</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Between February 1983 and January 1985, 206 laparoscopies were performed on 172 women following controlled ovarian hyperstimulation with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG). Sixty-four clinical pregnancies advanced beyond the sixth week of gestation and were confirmed by ultrasound; and 37.2% of the patients conceived after in vitro fertilization and embryo transfer. The clinical pregnancy rate was 31.1% when based on the number of laparoscopies performed and 33.9% when based on the number of embryo transfers. There were 12 multiple pregnancies (18.8%), 11 miscarriages (17.2%), and one ectopic (tubal) pregnancy (1.6%). The most important factors contributing toward the success of this program were the establishment of specific criteria for patient selection, rigid adherence to clinical and laboratory protocols, and the maintenance of strict quality control.</description><subject>Abortion, Spontaneous - epidemiology</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Chorionic Gonadotropin - pharmacology</subject><subject>Embryo Transfer</subject><subject>Female</subject><subject>Fertilization in Vitro</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infertility, Female - etiology</subject><subject>Infertility, Female - therapy</subject><subject>Laparoscopy</subject><subject>Medical sciences</subject><subject>Menotropins - pharmacology</subject><subject>Oocytes</subject><subject>Ovary - drug effects</subject><subject>Parity</subject><subject>Pregnancy</subject><subject>Pregnancy, Multiple</subject><subject>Pregnancy, Tubal - epidemiology</subject><subject>Quality Control</subject><subject>Sterility. Assisted procreation</subject><subject>Ultrasonography</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLw0AUhQdRaq3-BCELcTcwj2QebkRKq4WCmyq6CpPkho5OkjqTUOuvd6TB1eXc83HgnBM0pUpyzDh_O0VTQpjGUqXpOboI4YMQQoXmEzRhmmdS0Cm6X7XJq-19lyzB99bZH9Pbrk1MWyWLpvCHLtl404Ya_F2y2Xf4HYxPFt878BbaEi7RWW1cgKvxztDLcrGZP-H18-Nq_rDGO6ozhsuM1ZwYJoRSRDFjMlBCaakghZJxEDQKqAgHyouaVIUmdcmUlGUGVSUJn6HbY-7Od18DhD5vbCjBOdNCN4RcCqGlpjyC1yM4FA1U-c7bxvhDPjaO_s3om1AaV8dypQ3_WBwvI0xGLD1i-8714MOnG_bg8y0Y12_zOCQRLCOYaiUIjwr_vRj_BdVubgc</recordid><startdate>198603</startdate><enddate>198603</enddate><creator>SHER, GEOFFREY</creator><creator>KNUTZEN, VICTOR</creator><creator>STRATTON, CLIFFORD</creator><creator>CHOTINER, HAROLD</creator><creator>MAYVILLE, JACK</creator><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198603</creationdate><title>In Vitro Fertilization and Embryo Transfer: Two-Year Experience</title><author>SHER, GEOFFREY ; KNUTZEN, VICTOR ; STRATTON, CLIFFORD ; CHOTINER, HAROLD ; MAYVILLE, JACK</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1952-c52f30a26688082aa5e868978e4ec23e61897ed03e13bf0db90fc2877c5edd703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Abortion, Spontaneous - epidemiology</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Chorionic Gonadotropin - pharmacology</topic><topic>Embryo Transfer</topic><topic>Female</topic><topic>Fertilization in Vitro</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Infertility, Female - etiology</topic><topic>Infertility, Female - therapy</topic><topic>Laparoscopy</topic><topic>Medical sciences</topic><topic>Menotropins - pharmacology</topic><topic>Oocytes</topic><topic>Ovary - drug effects</topic><topic>Parity</topic><topic>Pregnancy</topic><topic>Pregnancy, Multiple</topic><topic>Pregnancy, Tubal - epidemiology</topic><topic>Quality Control</topic><topic>Sterility. Assisted procreation</topic><topic>Ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SHER, GEOFFREY</creatorcontrib><creatorcontrib>KNUTZEN, VICTOR</creatorcontrib><creatorcontrib>STRATTON, CLIFFORD</creatorcontrib><creatorcontrib>CHOTINER, HAROLD</creatorcontrib><creatorcontrib>MAYVILLE, JACK</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SHER, GEOFFREY</au><au>KNUTZEN, VICTOR</au><au>STRATTON, CLIFFORD</au><au>CHOTINER, HAROLD</au><au>MAYVILLE, JACK</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In Vitro Fertilization and Embryo Transfer: Two-Year Experience</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1986-03</date><risdate>1986</risdate><volume>67</volume><issue>3</issue><spage>309</spage><epage>315</epage><pages>309-315</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Between February 1983 and January 1985, 206 laparoscopies were performed on 172 women following controlled ovarian hyperstimulation with human menopausal gonadotropin (hMG) and human chorionic gonadotropin (hCG). Sixty-four clinical pregnancies advanced beyond the sixth week of gestation and were confirmed by ultrasound; and 37.2% of the patients conceived after in vitro fertilization and embryo transfer. The clinical pregnancy rate was 31.1% when based on the number of laparoscopies performed and 33.9% when based on the number of embryo transfers. There were 12 multiple pregnancies (18.8%), 11 miscarriages (17.2%), and one ectopic (tubal) pregnancy (1.6%). The most important factors contributing toward the success of this program were the establishment of specific criteria for patient selection, rigid adherence to clinical and laboratory protocols, and the maintenance of strict quality control.</abstract><cop>New York, NY</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>2935761</pmid><tpages>7</tpages></addata></record> |
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subjects | Abortion, Spontaneous - epidemiology Adult Biological and medical sciences Birth control Chorionic Gonadotropin - pharmacology Embryo Transfer Female Fertilization in Vitro Gynecology. Andrology. Obstetrics Humans Infant, Newborn Infertility, Female - etiology Infertility, Female - therapy Laparoscopy Medical sciences Menotropins - pharmacology Oocytes Ovary - drug effects Parity Pregnancy Pregnancy, Multiple Pregnancy, Tubal - epidemiology Quality Control Sterility. Assisted procreation Ultrasonography |
title | In Vitro Fertilization and Embryo Transfer: Two-Year Experience |
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