Isolation and characterisation of herpes simplex virus type 1 mutants which fail to induce dUTPase activity

The herpes simplex virus (HSV) type 1 dUTPase gene was inactivated by insertion of HindIII oligonucleotide linker sequences into the KpnI site within the coding region of the cloned gene. The mutated gene was introduced into wild type herpes simplex virus by marker rescue and the recombinants were i...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1986-01, Vol.148 (1), p.190-197
Hauptverfasser:	Fisher, Fiona B., Preston, Valerie G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Biological and medical sciences Cell Line Cricetinae Fundamental and applied biological sciences. Psychology Gene Expression Regulation Genetics herpes simplex virus 1 Kidney Mesocricetus Microbiology Pyrophosphatases - genetics Pyrophosphatases - physiology Recombinant Proteins - genetics Simplexvirus - enzymology Simplexvirus - genetics Simplexvirus - physiology Thymidine Kinase - genetics Thymidine Kinase - physiology Viral Proteins - genetics Viral Proteins - physiology Virology Virus Replication
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