Diagnosis of Creutzfeldt-Jakob Disease by Western Blot Identification of Marker Protein in Human Brain Tissue

We tested purified preparations of brain tissue from 39 patients with Creutzfeldt–Jakob disease, Gerstmann–Sträussler–Scheinker syndrome, or kuru, and from 32 patients with a variety of nonspongiform degenerative diseases, with the use of Western blots against an antiserum to a similarly purified fr...

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